Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.
ELIXIR-Hub, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom.
J Proteome Res. 2021 Apr 2;20(4):1821-1825. doi: 10.1021/acs.jproteome.0c00978. Epub 2021 Mar 15.
The large diversity of experimental methods in proteomics as well as their increasing usage across biological and clinical research has led to the development of hundreds if not thousands of software tools to aid in the analysis and interpretation of the resulting data. Detailed information about these tools needs to be collected, categorized, and validated to guarantee their optimal utilization. A tools registry like bio.tools enables users and developers to identify new tools with more powerful algorithms or to find tools with similar functions for comparison. Here we present the content of the registry, which now comprises more than 1000 proteomics tool entries. Furthermore, we discuss future applications and engagement with other community efforts resulting in a high impact on the bioinformatics landscape.
蛋白质组学中的实验方法种类繁多，而且在生物和临床研究中的应用也越来越广泛，这导致了数百种（如果不是数千种的话）软件工具的发展，以帮助分析和解释由此产生的数据。需要收集、分类和验证这些工具的详细信息，以保证它们得到最佳利用。像 bio.tools 这样的工具注册中心使用户和开发人员能够识别具有更强大算法的新工具，或者找到具有相似功能的工具进行比较。在这里，我们展示了注册表的内容，其中现在包含了超过 1000 个蛋白质组学工具条目。此外，我们还讨论了未来的应用和与其他社区努力的合作，这将对生物信息学领域产生重大影响。
