Sicree R A, Tuomilehto J, Zimmet P, King H, Ram P, Hunt D, Coventry J
WHO Collaborating Centre for the Epidemiology of Diabetes Mellitus, Royal Southern Memorial Hospital, Caulfield South, Australia.
Int J Cardiol. 1988 Apr;19(1):27-38. doi: 10.1016/0167-5273(88)90187-8.
Electrocardiograms were performed on 427 Melanesian and 391 Indian males aged 30-69 years surveyed in 1980. The age-adjusted prevalence of abnormalities in Minnesota coding suggesting coronary arterial disease was: Indians - 17.1%, Melanesians - 9.1%. This difference was significant at P less than 0.001. For the Melanesians body mass index, plasma uric acid, cholesterol and triglyceride and systolic blood pressure showed significant positive associations with electrocardiographic abnormalities in a univariate analysis, but only the plasma uric acid level was independently associated with such abnormalities following adjustment for these other factors in a multivariate analysis (P less than 0.001). For the Indians body mass index, systolic blood pressure, the presence of diabetes, urban residence and physical inactivity were positively associated with electrocardiographic abnormalities in the univariate analysis, but only body mass index (P less than 0.01), systolic blood pressure (P less than 0.01), and the 2-hour glucose level (P less than 0.01) were independently associated with such abnormalities when adjustment was made for the levels of the other factors.
1980年对427名年龄在30至69岁之间的美拉尼西亚男性和391名印度男性进行了心电图检查。根据明尼苏达编码,提示冠状动脉疾病的异常情况经年龄调整后的患病率为:印度人-17.1%,美拉尼西亚人-9.1%。这种差异在P小于0.001时具有统计学意义。对于美拉尼西亚人,在单因素分析中,体重指数、血浆尿酸、胆固醇、甘油三酯和收缩压与心电图异常呈显著正相关,但在多因素分析中对这些其他因素进行调整后,只有血浆尿酸水平与此类异常独立相关(P小于0.001)。对于印度人,在单因素分析中,体重指数、收缩压、糖尿病的存在、城市居住情况和身体活动不足与心电图异常呈正相关,但在对其他因素水平进行调整时,只有体重指数(P小于0.01)、收缩压(P小于0.01)和2小时血糖水平(P小于0.01)与此类异常独立相关。