慢性肾衰竭患者透析后心脏功能的变化。

Changes in cardiac performance after dialysis in patients with chronic renal failure.

作者信息

Takabatake H, Sasayama S, Fujita M, Asanoi H, Iida H

机构信息

Second Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Japan.

出版信息

Int J Cardiol. 1988 May;19(2):209-16. doi: 10.1016/0167-5273(88)90081-2.

DOI:10.1016/0167-5273(88)90081-2

PMID:3372081

Abstract

The effect of hemodialysis on left ventricular performance in 10 uremic patients was studied utilizing echocardiography. Left ventricular function curves constructed by a lower body negative pressure method were compared before and after dialysis. Although hemodialysis caused a decrease in the stroke volume index at rest from 55 +/- 17 to 50 +/- 20 ml/m2, the left ventricular function curve did not show any detectable shift. Thus, it is concluded that a decrease in stroke volume secondary to dialysis is attributable to the reduction in preload, rather than to changes in the contractile state of the left ventricle.

摘要

利用超声心动图研究了血液透析对10例尿毒症患者左心室功能的影响。通过下体负压法构建的左心室功能曲线在透析前后进行了比较。尽管血液透析使静息时的每搏量指数从55±17降至50±20ml/m²，但左心室功能曲线并未显示出任何可检测到的移位。因此，得出结论，透析继发的每搏量减少归因于前负荷的降低，而非左心室收缩状态的改变。