The Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Ramat-Gan, Israel; Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
The Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Ramat-Gan, Israel; Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Eur J Obstet Gynecol Reprod Biol. 2021 May;260:37-41. doi: 10.1016/j.ejogrb.2021.03.006. Epub 2021 Mar 10.
Data regarding the risks of obstetrical anal sphincter injury (OASI) among women who never delivered vaginally undergoing a trial of labor after cesarean (TOLAC) are scarce. We aimed to evaluate the risk factors and the rate of OASI among women undergoing TOLAC who never delivered vaginally.
A retrospective cohort study of all women undergoing a TOLAC and never delivered vaginally between 3/2011 and 6/2020. Maternal and intrapartum characteristics were compared between OASI and no-OASI groups. We matched groups to earliest gestational age in which OASI has occurred. A further comparison was made between the study cohort and a cohort of primiparous women undergoing a vaginal delivery, including gestational ages at which OASI has occurred in that cohort.
During the study period there were 2061 TOLACs among women without prior vaginal delivery. Of these, 76 % (1566/2061) had a successful vaginal delivery. Overall, 22/2061 (1.1 %) cases of OASI occurred. There was no difference in maternal demographic, obstetrical and medical history characteristics between the study groups. The mean gestational age at TOLAC was lower in the OASI group (39 ± 1 vs. 39 ± 1, p = 0.012). In multivariable regression analysis, gestational age was negatively associated with OASI [adjusted odds ratio, 95 % (confidence interval) 0.95 (0.91-0.99), for each day increase in gestational age)]. The rate of OASI in the study cohort did not differ from the rate of OASI among primiparous women during the same study period (347/27975, 1.2 %, p = 0.686).
Gestational age at delivery is the only predictor of OASI among women with no prior vaginal deliveries undergoing a TOLAC. The incidence of OASI in this population is 1.1 % and does not differ from that of primiparous women.
关于从未经阴道分娩的剖宫产术后试产(TOLAC)妇女中发生产科肛门括约肌损伤(OASI)的风险的数据很少。我们旨在评估 TOLAC 中从未经阴道分娩的妇女发生 OASI 的危险因素和发生率。
这是一项回顾性队列研究,纳入了 2011 年 3 月至 2020 年 6 月期间所有进行 TOLAC 且从未经阴道分娩的妇女。比较 OASI 组和无 OASI 组的产妇和产时特征。我们将两组匹配到最早发生 OASI 的孕龄。还将研究队列与一组经阴道分娩的初产妇进行了比较,包括该队列中发生 OASI 的孕龄。
在研究期间,有 2061 名 TOLAC 妇女从未经阴道分娩。其中,76%(1566/2061)成功阴道分娩。总的来说,2061 例中有 22 例(1.1%)发生 OASI。两组的产妇人口统计学、产科和病史特征无差异。OASI 组的 TOLAC 平均孕龄较低(39 ± 1 与 39 ± 1,p = 0.012)。多变量回归分析显示,孕龄与 OASI 呈负相关[调整后的优势比,95%置信区间(95%CI)0.95(0.91-0.99),孕龄每增加一天]。研究队列中的 OASI 发生率与同一时期初产妇的 OASI 发生率无差异(347/27975,1.2%,p = 0.686)。
对于从未经阴道分娩的 TOLAC 妇女,分娩时的孕龄是 OASI 的唯一预测因素。该人群的 OASI 发生率为 1.1%,与初产妇无差异。