Xu Pengpeng, Xue Yi, Schoepf U Joseph, Varga-Szemes Akos, Griffith Joseph, Yacoub Basel, Zhou Fan, Zhou Changsheng, Yang Yuting, Xing Wei, Zhang Longjiang
Department of Diagnostic Radiology, Jinling Hospital, Medical School of Nanjing University, Jiangsu, China (P.X., F.Z., C.Z., L.Z.).
Department of Diagnostic Radiology, Jinling Hospital, the First School of Clinical Medicine, Southern Medical University, Nanjing, Jiangsu Province, China (Y.X., Y.Y., L.Z.).
Circ Cardiovasc Imaging. 2021 Mar;14(3):e011747. doi: 10.1161/CIRCIMAGING.120.011747. Epub 2021 Mar 16.
Radiomics uses advanced image analysis to extract massive amounts of quantitative information from digital images, which is not otherwise distinguishable to the human eye. The mined data can be used to explore and establish new and undiscovered correlations between these imaging features and clinical end points. Cardiac computed tomography (CT) is a first-line imaging modality for evaluating coronary artery disease and has a primary role in the assessment of cardiac structures. Conventional interpretation of cardiac CT images relies mostly on subjective and qualitative analysis, as well as basic geometric quantification. To date, some proof-of-concept studies have demonstrated the feasibility and diagnostic performance of cardiac CT radiomics analysis. This review describes the current literature on radiomics in cardiac CT and discusses its advantages, challenges, and future directions. Although much evidences are needed in this field, cardiac CT radiomics has a lot to offer to patients and physicians with potential to define cardiac disease phenotypes on imaging with higher precision.
放射组学利用先进的图像分析技术从数字图像中提取大量定量信息，这些信息是人眼无法分辨的。挖掘出的数据可用于探索并建立这些成像特征与临床终点之间新的、未被发现的关联。心脏计算机断层扫描（CT）是评估冠状动脉疾病的一线成像方式，在心脏结构评估中起主要作用。心脏CT图像的传统解读主要依赖主观和定性分析以及基本的几何量化。迄今为止，一些概念验证研究已经证明了心脏CT放射组学分析的可行性和诊断性能。本综述描述了关于心脏CT放射组学的当前文献，并讨论了其优势、挑战和未来方向。尽管该领域还需要大量证据，但心脏CT放射组学有很大潜力为患者和医生提供帮助，有可能在成像上更精确地定义心脏疾病表型。
