The Department of General Surgery and The Bariatric and Metabolic Institute at Cleveland Clinic, Weston, Florida.
The Department of General Surgery and The Bariatric and Metabolic Institute at Cleveland Clinic, Weston, Florida.
Surg Obes Relat Dis. 2021 Apr;17(4):799-814. doi: 10.1016/j.soard.2020.10.027. Epub 2020 Nov 2.
Gastroparesis (GPS) is a rare disease with multiple etiologies that results in delayed gastric emptying. Diagnosis of GPS can be challenging due to its rather complex clinical presentation. Pharmacologic refractory cases require surgical interventions, all of which have yet to be standardized and characterized.
We present a review of the literature and provide an update of current therapies for patients with GPS.
Department of General Surgery, Academic Hospital, United States.
We conducted a comprehensive search in PubMed, Google Scholar, and Embase of English-written articles published in the last 38 years, with an advance title search of "gastroparesis management." Other keywords included: "surgical management" and "refractory gastroparesis." Further references were obtained through cross-reference.
A total of 12,250 articles were selected after eliminating duplicates. Following thorough screening of selection criteria, 68 full-text articles were included for review.
GPS is a challenging disease to manage. Nutritional support must remain the primary approach, followed by either medical or surgical treatment modalities if necessary. In patients with refractory gastroparesis, adjunctive therapies have been proposed as promising long-term options.
胃轻瘫（GPS）是一种罕见的疾病，有多种病因导致胃排空延迟。由于其临床表现较为复杂，GPS 的诊断具有一定挑战性。药物难治性病例需要手术干预，但所有这些都尚未标准化和确定特征。
我们对文献进行了综述，并为 GPS 患者提供了目前治疗方法的最新信息。
美国学术医院普通外科系。
我们在 PubMed、Google Scholar 和 Embase 上全面检索了过去 38 年发表的英文文章，并对“胃轻瘫管理”进行了提前标题搜索。其他关键词包括：“手术管理”和“难治性胃轻瘫”。通过交叉引用获得了更多参考文献。
在消除重复项后，共筛选出 12250 篇文章。经过仔细筛选选择标准后，纳入了 68 篇全文进行综述。
GPS 是一种具有挑战性的疾病。营养支持必须仍然是主要方法，如果需要，可采用药物或手术治疗方法。对于药物难治性胃轻瘫患者，已经提出了辅助治疗方法作为有前途的长期选择。
