Department of Radiation Oncology, Jaypee Hospital, Noida; Department of Radiation Oncology, Max Super Specialty Hospital, Vaishali, Uttar Pradesh, India.
Department of Radiation Oncology, Max Super Specialty Hospital, Patparganj, Delhi, India.
J Cancer Res Ther. 2021 Jan-Mar;17(1):152-156. doi: 10.4103/jcrt.JCRT_626_18.
Organ motion is an important factor that limits the precision of radiation treatment. Bladder filling variation has significant impact on the position of target volumes in pelvic malignancies.
This study was an effort to maintain a consistent urinary bladder volume after following a bladder protocol, which was then analyzed by in-room cone-beam computed tomography (CBCT) imaging.
A total number of 26 patients/300 scans, i.e. 26 planning scan and 274 CBCT were analyzed. The bladder volumes and bladder wall dimension were analyzed comprehensively, thus adding considerable understanding to the bladder wall motions.
The mean bladder volume for all 26 patients was 183.07 cc with standard deviation of 90.43 cc. The mean +/- standard deviation of transverse, anteroposterior and longitudinal diameter was 8.35+/- 1.03, 6.69+/-1.05 and 5.59+/-1.79 cm.
This study showed considerable reduction of margin could be done on the lateral side, as there is less displacement on transverse diameter and more liberal margins should be considered in anteroposterior dimension and longitudinal dimensions. This study has reached the conclusion that bladder-filling protocol is necessary to maintain the consistent bladder volume, but it is too preliminary to state that it will translate into reduction of margin.
器官运动是限制放射治疗精度的一个重要因素。在骨盆恶性肿瘤中，膀胱充盈变化对靶区位置有显著影响。
本研究旨在遵循膀胱方案后保持膀胱体积一致，并通过机房锥形束 CT（CBCT）成像进行分析。
共分析了 26 名患者/300 次扫描，即 26 次计划扫描和 274 次 CBCT。全面分析了膀胱体积和膀胱壁尺寸，从而对膀胱壁运动有了更深入的了解。
26 名患者的平均膀胱体积为 183.07cc，标准差为 90.43cc。横向、前后和纵向直径的平均值分别为 8.35+/-1.03、6.69+/-1.05 和 5.59+/-1.79cm。
本研究表明，在横向方向上可以减少更大的边缘，因为横向直径的位移较小，而在前后和纵向方向上应该考虑更大的边缘。本研究得出的结论是，膀胱充盈方案对于保持膀胱体积一致是必要的，但要说明它将转化为减少边缘还为时过早。
