Vicini D S, Wheaton L G, Zachary J F, Parker A J
Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana 61801.
J Am Vet Med Assoc. 1988 Apr 15;192(8):1087-90.
Saphenous nerve biopsy was performed to diagnose globoid cell leukodystrophy in a 3-month-old West Highland White Terrier. The dog had progressive neurologic disease that appeared to involve the cerebellum, spinal cord, and lower motor neurons to the hind limbs. Light and transmission electron microscopic findings of the nerve biopsy specimen established the diagnosis. Peripheral nerve biopsy may provide a reliable antemortem method for diagnosis of globoid cell leukodystrophy.
