• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一组接受现代全膝关节置换术(TKA)方案治疗的 TKA 患者的平均麻醉药物使用量。

Average narcotic usage in a group of TKA patients following a modern TKA protocol.

机构信息

University of Maryland Medical Center, 110 South Paca Street 6(th) Floor Suite 300, Baltimore, MD 21201, United States.

The University of Maryland St. Joseph Medical Center, 7601 Osler Dr., Towson, MD 21204, United States.

出版信息

Knee. 2021 Mar;29:426-431. doi: 10.1016/j.knee.2021.02.032. Epub 2021 Mar 13.

DOI:10.1016/j.knee.2021.02.032
PMID:33725664
Abstract

INTRODUCTION

The optimal dosing of post-operative total knee arthroplasty (TKA) narcotics is unclear. We report on the average narcotic usage in a group of patients treated with an identical multimodal pain protocol following TKA.

MATERIALS AND METHODS

49 patients undergoing TKA participated in the survey. Patients with pre-op narcotic use, recent prior total joint arthroplasty or study refusal were excluded. All patients received a spinal anesthetic. No pre-surgery narcotics were given. All received an identical local infiltrative anesthetic combination along with a multimodal pain protocol. Patients were placed into an identical rapid rehab program. Narcotic usage during hospitalization was recorded in morphine equivalent doses (MED). Patients were given a journal to record their daily narcotic utilization.

RESULTS

Pre-operative pain scores of the excluded groups had slightly higher but clinically insignificant differences compared to the study group. In the hospital, POD1 study group daily MED averaged 28 (range 0-110). POD2 had an average of 33.6 and POD 3 daily usages averaged 28.6 (range 0-100). By the end of week two, the average daily use was 19.2 and 24% patients were off all narcotics. By the end of week four, the average daily usage was 7.5 and 63% of patients were off all narcotics. By 8 weeks, there were no patients still taking narcotics. KSS averaged 76.9 (range 51-97) at the 6 week visit, and 94.2 at the 3-month visit (range 72-100).

SUMMARY

This study documents the average needs of an average TKA patient treated with modern pain protocols. The majority of these patients were off narcotics by week four.

摘要

引言

全膝关节置换术后(TKA)阿片类药物的最佳剂量尚不清楚。我们报告了一组接受相同多模式疼痛方案治疗的 TKA 患者的平均阿片类药物使用情况。

材料和方法

49 例接受 TKA 的患者参与了这项调查。排除术前使用阿片类药物、近期接受过全关节置换术或拒绝研究的患者。所有患者均接受了脊髓麻醉。术前未给予任何阿片类药物。所有患者均接受了相同的局部浸润性麻醉联合多模式疼痛方案。患者被纳入相同的快速康复计划。住院期间记录吗啡等效剂量(MED)的阿片类药物使用量。患者记录了他们的每日阿片类药物使用情况。

结果

排除组的术前疼痛评分略高,但与研究组相比差异无统计学意义。在医院,第 1 天(POD1)研究组的平均每日 MED 为 28(范围 0-110)。第 2 天(POD2)平均为 33.6,第 3 天(POD3)平均为 28.6(范围 0-100)。在第 2 周结束时,平均每日使用量为 19.2,24%的患者停止使用所有阿片类药物。在第 4 周结束时,平均每日使用量为 7.5,63%的患者停止使用所有阿片类药物。第 8 周时,没有患者仍在服用阿片类药物。第 6 周时 KSS 平均为 76.9(范围 51-97),第 3 个月时为 94.2(范围 72-100)。

总结

本研究记录了接受现代疼痛方案治疗的普通 TKA 患者的平均需求。大多数患者在第 4 周时已停止使用阿片类药物。

相似文献

1
Average narcotic usage in a group of TKA patients following a modern TKA protocol.一组接受现代全膝关节置换术(TKA)方案治疗的 TKA 患者的平均麻醉药物使用量。
Knee. 2021 Mar;29:426-431. doi: 10.1016/j.knee.2021.02.032. Epub 2021 Mar 13.
2
Opioid Use After Discharge Following Primary Unilateral Total Knee Arthroplasty: How Much Are We Over-Prescribing?初次单侧全膝关节置换术后出院后的阿片类药物使用:我们的处方是否过度?
J Arthroplasty. 2020 Jun;35(6S):S158-S162. doi: 10.1016/j.arth.2020.01.078. Epub 2020 Feb 5.
3
Intraoperative Ketamine in Total Knee Arthroplasty Does Not Decrease Pain and Narcotic Consumption: A Prospective Randomized Controlled Trial.全膝关节置换术中使用氯胺酮并不会降低疼痛和阿片类药物的消耗:一项前瞻性随机对照试验。
J Arthroplasty. 2019 Aug;34(8):1640-1645. doi: 10.1016/j.arth.2019.04.017. Epub 2019 Apr 12.
4
A Multi-institutional Assessment of Multimodal Analgesia in Penile Implant Recipients Demonstrates Dramatic Reduction in Pain Scores and Narcotic Usage.多模式镇痛在阴茎植入患者中的多机构评估显示疼痛评分和麻醉药物使用量显著降低。
J Sex Med. 2020 Mar;17(3):518-525. doi: 10.1016/j.jsxm.2019.11.267. Epub 2019 Dec 20.
5
Preoperative Opiate Use Independently Predicts Narcotic Consumption and Complications After Total Joint Arthroplasty.术前使用阿片类药物可独立预测全关节置换术后的麻醉药物消耗量及并发症。
J Arthroplasty. 2017 Sep;32(9):2658-2662. doi: 10.1016/j.arth.2017.04.002. Epub 2017 Apr 12.
6
Narcotic Consumption in Opioid-Naïve Patients Undergoing Total Hip and Knee Arthroplasty.阿片类药物初治患者行全髋关节和全膝关节置换术后的阿片类药物消耗。
J Arthroplasty. 2020 Sep;35(9):2392-2396. doi: 10.1016/j.arth.2020.04.089. Epub 2020 May 4.
7
Intravenous vs Oral Acetaminophen as an Adjunct to Multimodal Analgesia After Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind Clinical Trial.全膝关节置换术后静脉注射与口服对乙酰氨基酚作为多模式镇痛辅助用药的前瞻性、随机、双盲临床试验
J Arthroplasty. 2017 Oct;32(10):3029-3033. doi: 10.1016/j.arth.2017.05.019. Epub 2017 May 18.
8
Increased postoperative dexamethasone and gabapentin reduces opioid consumption after total knee arthroplasty.术后增加地塞米松和加巴喷丁可减少全膝关节置换术后阿片类药物的消耗。
Knee Surg Sports Traumatol Arthrosc. 2019 Jul;27(7):2167-2172. doi: 10.1007/s00167-019-05449-8. Epub 2019 Mar 2.
9
Periarticular Injection of Liposomal Bupivacaine Offers No Benefit Over Standard Bupivacaine in Total Knee Arthroplasty: A Prospective, Randomized, Controlled Trial.在全膝关节置换术中,关节周围注射脂质体布比卡因并不比标准布比卡因更具优势:一项前瞻性、随机、对照试验。
J Arthroplasty. 2017 Feb;32(2):628-634. doi: 10.1016/j.arth.2016.07.023. Epub 2016 Aug 9.
10
Novel Multi-Modal Analgesia Protocol Significantly Decreases Opioid Requirements in Inflatable Penile Prosthesis Patients.新型多模式镇痛方案显著降低了可充气阴茎假体患者的阿片类药物需求。
J Sex Med. 2018 Aug;15(8):1187-1194. doi: 10.1016/j.jsxm.2018.05.017. Epub 2018 Jul 13.