Fang D, Leong J C, Ho E K, Chan F L, Chow S P
University of Hong Kong.
J Bone Joint Surg Br. 1988 May;70(3):443-7. doi: 10.1302/0301-620X.70B3.3372569.
We reviewed 40 extensive destructive vertebral lesions in 35 patients with established ankylosing spondylitis. Of these, 31 had presented with localised pain while three had a neurological deficit. The radiographs suggested ununited fractures through either ankylosed discs (37) or vertebral bodies (3). Corresponding fractures were seen in the posterior column in 34 cases. Sixteen patients with 18 lesions underwent anterior spinal fusion, and pseudarthrosis was consistently proven by histopathology. Two pseudarthroses healed in conservatively treated patients. Thirteen of the operated patients were followed for an average of 7 years 7 months. There were two cases of non-union and one required an additional posterior fusion; in the remainder fusion was sound.
我们回顾了35例确诊为强直性脊柱炎患者的40处广泛性破坏性椎体病变。其中，31例表现为局部疼痛，3例有神经功能缺损。X线片显示骨折不愈合，骨折部位通过融合的椎间盘（37处）或椎体（3处）。34例患者后柱可见相应骨折。16例有18处病变的患者接受了前路脊柱融合术，组织病理学证实均存在假关节形成。2例假关节在保守治疗的患者中愈合。13例接受手术的患者平均随访7年7个月。有2例骨不连，1例需要额外进行后路融合；其余患者融合良好。
