Department of Pharmacy, Evidence-based Pharmacy Center, West China second hospital, Sichuan University. Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education.
Department of Epidemiology, West China School of Public Health, and West China Fourth Hospital, Sichuan University.
Medicine (Baltimore). 2021 Mar 12;100(10):e23571. doi: 10.1097/MD.0000000000023571.
This study investigated the epidemiological status of depression and its influencing factors among caregivers of children with epilepsy in southwestern China.This was a cross-sectional study. Caregivers of children with epilepsy were recruited from February to June 2018 at the Pediatric Neurology Department of the West China Second Hospital. Depression status was assessed using the Zung Self-Rating Depression Scale. Multiple linear regression analysis was used to assess correlations between depression status and its influencing factors.A total of 319 participants were included. The mean Zung Self-Rating Depression Scale score was 36.37 ± 10.178 and 5.3% (17/319) of participants were classified as depressed. Regression analysis showed that place of residence (B = 0.114; standard error = 0.643; P = .039), attitude towards seizures (B = -0.121; standard error = 1.215; P = .029), medical expenses payment (B = -0.111; standard error = 2.002; P = .044), and children's medication adherence (B = -0.124; standard error = 0.393; P = .025) were related to depression.Some caregivers of children with epilepsy in southwestern China experience depression. Health care providers should pay particular attention to caregivers who live in rural areas, who fear seizures, who experience difficulty paying medical expenses, and whose children show low medication adherence.
本研究调查了中国西南部癫痫患儿照顾者的抑郁状况及其影响因素。这是一项横断面研究。2018 年 2 月至 6 月,在华西第二医院儿科神经科招募了癫痫患儿的照顾者。使用zung 自评抑郁量表评估抑郁状况。采用多元线性回归分析评估抑郁状况及其影响因素之间的相关性。共纳入 319 名参与者。zung 自评抑郁量表平均得分为 36.37±10.178,5.3%(17/319)的参与者被诊断为抑郁。回归分析显示,居住地点(B=0.114;标准误=0.643;P=0.039)、对癫痫发作的态度(B=-0.121;标准误=1.215;P=0.029)、医疗费用支付(B=-0.111;标准误=2.002;P=0.044)和儿童用药依从性(B=-0.124;标准误=0.393;P=0.025)与抑郁有关。中国西南部一些癫痫患儿的照顾者存在抑郁。医疗保健提供者应特别关注居住在农村地区、害怕癫痫发作、医疗费用支付困难和儿童用药依从性低的照顾者。