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表现为坐骨神经痛的慢性未确诊布鲁氏菌病

Chronic Undiagnosed Brucellosis Presenting as Sciatica.

作者信息

Rozis Meletis, Vlamis John, Pneumaticos Spyros G

机构信息

3rd Orthopaedic Department, University of Athens, KAT Hospital, Athens, GRC.

出版信息

Cureus. 2021 Feb 3;13(2):e13114. doi: 10.7759/cureus.13114.

Abstract

Brucellosis is a common zoonotic disease in southern Europe. Although having the potential to harm several anatomic regions and systems, musculoskeletal manifestations are rare, usually involving the spine and the sacroiliac joints. In the literature, the reports of hip manifestations are sporadic. We present a case report of chronic, undiagnosed brucellosis indirectly affecting the hip joint. A 51-years-old male patient was admitted to our department with acute onset sciatica. His medical history was remarkable for incomplete cauda equina syndrome of unknown etiology and concomitant dura mater disruption, creating local sinuses resulting at the right buttock. On radiological evaluation, we demonstrated multiple abscesses of the lower lumbar spine and the ipsilateral sacroiliac joint, along with sinuses communicating with the right hip joint capsule. Soft and osseous tissue cultures obtained from the area of the lesion were negative for common bacteria. Considering the patient's history, chronicity of the disease, and the lesional pattern, we suspected brucellosis as a possible etiological factor. Laboratory evaluation with the serum agglutination test confirmed the diagnosis. The patient denied the surgical treatment, so we proceeded with chronic suppression antibiotics schemes. On 12-month follow-up, the patient has no clinical signs of infection relapse; he has reasonable pain control and a normal gait. Indirect hip infection due to chronic brucellosis is rare, and physicians should be very suspicious of the disease's characteristic radiological manifestations to reach a correct diagnosis.

摘要

布鲁氏菌病是南欧一种常见的人畜共患病。尽管布鲁氏菌病有可能损害多个解剖区域和系统,但肌肉骨骼表现较为罕见,通常累及脊柱和骶髂关节。在文献中,关于髋关节表现的报道较为零散。我们报告一例慢性、未确诊的布鲁氏菌病间接影响髋关节的病例。一名51岁男性患者因急性坐骨神经痛入院。他的病史以病因不明的不完全马尾综合征及伴随的硬脑膜破裂为显著特征,导致右侧臀部出现局部窦道。经影像学评估,我们发现下腰椎和同侧骶髂关节有多个脓肿,以及与右髋关节囊相通的窦道。从病变部位获取的软组织和骨组织培养物未检出常见细菌。考虑到患者的病史、疾病的慢性病程以及病变模式,我们怀疑布鲁氏菌病是可能的病因。血清凝集试验的实验室评估确诊了该诊断。患者拒绝手术治疗,因此我们采用了慢性抑制性抗生素方案。在12个月的随访中,患者没有感染复发的临床迹象;疼痛得到合理控制,步态正常。慢性布鲁氏菌病引起的间接髋关节感染很少见,医生应高度怀疑该病的特征性影像学表现以做出正确诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/c3cb1f3f5cf7/cureus-0013-00000013114-i01.jpg

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