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表现为坐骨神经痛的慢性未确诊布鲁氏菌病

Chronic Undiagnosed Brucellosis Presenting as Sciatica.

作者信息

Rozis Meletis, Vlamis John, Pneumaticos Spyros G

机构信息

3rd Orthopaedic Department, University of Athens, KAT Hospital, Athens, GRC.

出版信息

Cureus. 2021 Feb 3;13(2):e13114. doi: 10.7759/cureus.13114.

DOI:10.7759/cureus.13114
PMID:33728133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7936015/
Abstract

Brucellosis is a common zoonotic disease in southern Europe. Although having the potential to harm several anatomic regions and systems, musculoskeletal manifestations are rare, usually involving the spine and the sacroiliac joints. In the literature, the reports of hip manifestations are sporadic. We present a case report of chronic, undiagnosed brucellosis indirectly affecting the hip joint. A 51-years-old male patient was admitted to our department with acute onset sciatica. His medical history was remarkable for incomplete cauda equina syndrome of unknown etiology and concomitant dura mater disruption, creating local sinuses resulting at the right buttock. On radiological evaluation, we demonstrated multiple abscesses of the lower lumbar spine and the ipsilateral sacroiliac joint, along with sinuses communicating with the right hip joint capsule. Soft and osseous tissue cultures obtained from the area of the lesion were negative for common bacteria. Considering the patient's history, chronicity of the disease, and the lesional pattern, we suspected brucellosis as a possible etiological factor. Laboratory evaluation with the serum agglutination test confirmed the diagnosis. The patient denied the surgical treatment, so we proceeded with chronic suppression antibiotics schemes. On 12-month follow-up, the patient has no clinical signs of infection relapse; he has reasonable pain control and a normal gait. Indirect hip infection due to chronic brucellosis is rare, and physicians should be very suspicious of the disease's characteristic radiological manifestations to reach a correct diagnosis.

摘要

布鲁氏菌病是南欧一种常见的人畜共患病。尽管布鲁氏菌病有可能损害多个解剖区域和系统,但肌肉骨骼表现较为罕见,通常累及脊柱和骶髂关节。在文献中,关于髋关节表现的报道较为零散。我们报告一例慢性、未确诊的布鲁氏菌病间接影响髋关节的病例。一名51岁男性患者因急性坐骨神经痛入院。他的病史以病因不明的不完全马尾综合征及伴随的硬脑膜破裂为显著特征,导致右侧臀部出现局部窦道。经影像学评估,我们发现下腰椎和同侧骶髂关节有多个脓肿,以及与右髋关节囊相通的窦道。从病变部位获取的软组织和骨组织培养物未检出常见细菌。考虑到患者的病史、疾病的慢性病程以及病变模式,我们怀疑布鲁氏菌病是可能的病因。血清凝集试验的实验室评估确诊了该诊断。患者拒绝手术治疗,因此我们采用了慢性抑制性抗生素方案。在12个月的随访中,患者没有感染复发的临床迹象;疼痛得到合理控制,步态正常。慢性布鲁氏菌病引起的间接髋关节感染很少见,医生应高度怀疑该病的特征性影像学表现以做出正确诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/4c864045ac55/cureus-0013-00000013114-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/c3cb1f3f5cf7/cureus-0013-00000013114-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/5b0d80c27688/cureus-0013-00000013114-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/b825a151d2e9/cureus-0013-00000013114-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/f4e50c6b482a/cureus-0013-00000013114-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/5bbf56099a53/cureus-0013-00000013114-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/4ec85863f0ad/cureus-0013-00000013114-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/217ae8ea15f5/cureus-0013-00000013114-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/85df92ccf81d/cureus-0013-00000013114-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/4c864045ac55/cureus-0013-00000013114-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/c3cb1f3f5cf7/cureus-0013-00000013114-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/5b0d80c27688/cureus-0013-00000013114-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/b825a151d2e9/cureus-0013-00000013114-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/f4e50c6b482a/cureus-0013-00000013114-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/5bbf56099a53/cureus-0013-00000013114-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/4ec85863f0ad/cureus-0013-00000013114-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/217ae8ea15f5/cureus-0013-00000013114-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/85df92ccf81d/cureus-0013-00000013114-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2469/7936015/4c864045ac55/cureus-0013-00000013114-i09.jpg

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本文引用的文献

1
A Systematic Review and Meta-Analysis of Epidemiology and Clinical Manifestations of Human Brucellosis in China.一项中国布鲁氏菌病流行病学和临床表现的系统评价和荟萃分析。
Biomed Res Int. 2018 Apr 22;2018:5712920. doi: 10.1155/2018/5712920. eCollection 2018.
2
Effect of hydroxychloroquine on treatment and recurrence of acute brucellosis: a single-blind, randomized clinical trial.羟氯喹对急性布鲁氏菌病治疗和复发的影响:一项单盲、随机临床试验。
Int J Antimicrob Agents. 2018 Mar;51(3):365-369. doi: 10.1016/j.ijantimicag.2017.08.009. Epub 2017 Aug 4.
3
Single-stage transforaminal decompression, debridement, interbody fusion, and posterior instrumentation for lumbosacral brucellosis.
一期经椎间孔减压、清创、椎间融合及后路内固定治疗腰骶部布鲁氏菌病
BMC Surg. 2017 Jul 14;17(1):82. doi: 10.1186/s12893-017-0279-x.
4
Celecoxib for the treatment of mild-to-moderate depression due to acute brucellosis: a double-blind, placebo-controlled, randomized trial.塞来昔布治疗急性布鲁氏菌病所致轻至中度抑郁症:一项双盲、安慰剂对照的随机试验。
J Clin Pharm Ther. 2015 Aug;40(4):441-6. doi: 10.1111/jcpt.12287. Epub 2015 May 26.
5
Magnetic resonance imaging findings of musculoskeletal brucellosis.肌肉骨骼型布鲁氏菌病的磁共振成像表现
Clin Imaging. 2014 Sep-Oct;38(5):719-23. doi: 10.1016/j.clinimag.2014.04.007. Epub 2014 Apr 21.
6
Update on treatment options for spinal brucellosis.脊柱布鲁氏菌病治疗选择的最新进展。
Clin Microbiol Infect. 2014 Feb;20(2):O75-82. doi: 10.1111/1469-0691.12351. Epub 2013 Oct 1.
7
Treatment of brucellosis: a systematic review of studies in recent twenty years.布鲁氏菌病的治疗:对近二十年研究的系统评价
Caspian J Intern Med. 2013 Spring;4(2):636-41.
8
Brucellosis-induced avascular necrosis of the hip in a middle-aged person.中年患者布鲁氏菌病诱发的髋部缺血性坏死
Iran J Public Health. 2012 Dec 1;41(12):86-8. Print 2012.
9
The spectrum of imaging findings of brucellosis: a pictorial essay.
Can Assoc Radiol J. 2012 Feb;63(1):5-11. doi: 10.1016/j.carj.2010.09.011. Epub 2010 Nov 12.
10
Perspectives for the treatment of brucellosis in the 21st century: the Ioannina recommendations.21世纪布鲁氏菌病的治疗前景:约阿尼纳建议
PLoS Med. 2007 Dec;4(12):e317. doi: 10.1371/journal.pmed.0040317.