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胸腰椎爆裂骨折后路固定策略的比较:有限元研究。

Comparison of Posterior Fixation Strategies for Thoracolumbar Burst Fracture: A Finite Element Study.

机构信息

Section of Neurosurgery, Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.

Department of Civil Engineering, National Cheng Kung University, Tainan 701, Taiwan; Department of Civil and Disaster Prevention Engineering, National United University, Miaoli 360, Taiwan.

出版信息

J Biomech Eng. 2021 Jul 1;143(7). doi: 10.1115/1.4050537.

Abstract

The management of thoracolumbar (TL) burst fractures remained challenging. Due to the complex nature of the fractured vertebrae and the lack of clinical and biomechanical evidence, currently, there was still no guideline to select the optimal posterior fixation strategy for TL burst fracture. We utilized a T10-L3 TL finite element model to simulate L1 burst fracture and four surgical constructs with one- or two-level suprajacent and infrajacent instrumentation (U1L1, U1L2, U2L1, and U2L2). This study was aimed to compare the biomechanical properties and find an optimal fixation strategy for TL burst fracture in order to minimize motion in the fractured level without exerting significant burden in the construct. Our result showed that two-level infrajacent fixation (U1L2 and U2L2) resulted in greater global motion reduction ranging from 66.0 to 87.3% compared to 32.0 to 47.3% in one-level infrajacent fixation (U1L1 and U2L1). Flexion produced the largest pathological motion in the fractured level but the differences between the constructs were small, all within 0.26 deg. Comparisons in implant stress showed that U2L1 and U2L2 had an average 25.3 and 24.8% less von Mises stress in the pedicle screws compared to U1L1 and U1L2, respectively. The construct of U2L1 had better preservation of the physiological spinal motion while providing sufficient range of motion reduction at the fractured level. We suggested that U2L1 is a good alternative to the standard long-segment fixation with better preservation of physiological motion and without an increased risk of implant failure.

摘要

胸腰椎(TL)爆裂骨折的治疗仍然具有挑战性。由于骨折椎体的复杂性以及缺乏临床和生物力学证据,目前仍然没有指南可以选择治疗 TL 爆裂骨折的最佳后路固定策略。我们使用 T10-L3 TL 有限元模型模拟 L1 爆裂骨折和四种手术结构,包括一个或两个节段的上位和下位固定(U1L1、U1L2、U2L1 和 U2L2)。本研究旨在比较生物力学特性,为 TL 爆裂骨折寻找最佳的固定策略,以最小化骨折节段的活动度,同时不对固定结构施加显著的负担。我们的结果表明,与下位单节段固定(U1L1 和 U2L1)相比,下位双节段固定(U1L2 和 U2L2)可使整体运动减少 66.0%至 87.3%,而仅下位单节段固定可使整体运动减少 32.0%至 47.3%。屈曲产生的骨折节段的病理性运动最大,但各结构之间的差异较小,均在 0.26°以内。植入物应力比较显示,与 U1L1 和 U1L2 相比,U2L1 和 U2L2 的椎弓根螺钉的平均 von Mises 应力分别减少了 25.3%和 24.8%。U2L1 结构在保持生理脊柱运动的同时,提供了足够的骨折节段活动度减少,具有更好的保留生理运动的特点。我们建议 U2L1 是标准长节段固定的良好替代方案,可更好地保留生理运动,且不会增加植入物失效的风险。

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