连续血糖监测与 1 型糖尿病青年患者的血糖控制：即使是最简单的胰岛素给药方法也有益处。
Continuous Glucose Monitoring and Glycemic Control in Young Adults with Type 1 Diabetes: Benefit for Even the Simplest Insulin Administration Methods.
机构信息
Joslin Diabetes Center, Boston, Massachusetts, USA.
Harvard Medical School, Boston, Massachusetts, USA.
出版信息
Diabetes Technol Ther. 2021 Aug;23(8):586-589. doi: 10.1089/dia.2020.0624.
The impact of continuous glucose monitoring (CGM) on glycemic control in young adults with type 1 diabetes (T1D) is controversial. Data from 888 young adults with T1D were reviewed (ages 18-30 years, 52% female, glycated hemoglobin [HbA1c] 8.1% ± 1.5%). Prescription of CGM was recorded for 54% of young adults; 66% were pump users, 46% on insulin injections and carbohydrate (carb) counting, and 32% on insulin doses without carb counting ( ≤ 0.001). HbA1c was lower in young adults with CGM versus no CGM (7.7% ± 1.3% vs. 8.2% ± 1.7%, ≤ 0.001). Difference in HbA1c between CGM versus no CGM was greater in young adults noncarb counting (7.9% ± 1.4% vs. 8.9% ± 2.3%, = 0.002) than carb counting (7.7% ± 1.5% vs. 8.2% ± 1.7%, = 0.0008), or pump users (7.6 ± 1.2 vs. 7.9 ± 1.1, = 0.01). Prescription of CGM was higher with increasing complexity of insulin regimens; however, impact of CGM was greatest with simpler insulin administration methods. Further studies are needed to clarify this association.
连续血糖监测（CGM）对 1 型糖尿病（T1D）年轻患者血糖控制的影响存在争议。本研究回顾了 888 例 T1D 年轻患者的数据（年龄 18-30 岁，52%为女性，糖化血红蛋白 [HbA1c] 8.1%±1.5%）。记录了 54%的年轻患者 CGM 的使用情况；66%为胰岛素泵使用者，46%接受胰岛素注射和碳水化合物（carb）计数，32%接受无 carb 计数的胰岛素剂量（ ≤ 0.001）。与无 CGM 相比，有 CGM 的年轻患者的 HbA1c 更低（7.7%±1.3%比 8.2%±1.7%， ≤ 0.001）。在不进行 carb 计数的年轻患者中，CGM 与无 CGM 相比，HbA1c 的差异更大（7.9%±1.4%比 8.9%±2.3%， = 0.002），而在进行 carb 计数的年轻患者中（7.7%±1.5%比 8.2%±1.7%， = 0.0008）或胰岛素泵使用者（7.6±1.2 比 7.9±1.1， = 0.01）中差异较小。胰岛素方案越复杂，CGM 的处方就越高；然而，CGM 的影响在胰岛素给药方法更简单时最大。需要进一步的研究来阐明这种关联。
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