Martin Tamás, Dank Magdolna, Biró Krisztina, Küronya Zsófia, Gyergyay Fruzsina, Nagyiványi Krisztián, Budai Barna, Fűrész Katinka, Géczi Lajos
Országos Onkológiai Intézet, Budapest, Hungary.
Onkológiai Központ, Semmelweis Egyetem, Budapest, Hungary.
Magy Onkol. 2021 Mar 17;65(1):53-57. Epub 2019 Aug 14.
Germ cell tumors of the testicle account for 1% of all tumors. Testicular cancer (TC) is the most common malignancy in men aged 15-35 years. Patients with TC have an excellent survival rate but often have not yet attempted to father children, and fertility is one of the main concerns of survivors, therefore it is important to preserve it. The most commonly used method is sperm banking. Retrospective analysis of the Hungarian data showed that in case of testicular cancer spermatogenesis is more impaired in the more advanced disease. No correlation was found among the histological types and the proportion of azoo- and oligozoospermia. The parameters of testicular cancer and non-Hodgkin lymphoma patients were worse compared to the normal population. Sperm cryopreservation prior to initiating life-saving cancer treatment offers men the best chance to father children and should be offered to all men with testicular cancer before chemotherapy, since cytostatic therapy may lead to infertility.
睾丸生殖细胞肿瘤占所有肿瘤的1%。睾丸癌（TC）是15至35岁男性中最常见的恶性肿瘤。TC患者的生存率很高，但往往尚未尝试生育子女，生育能力是幸存者主要关注的问题之一，因此保留生育能力很重要。最常用的方法是精子库保存。对匈牙利数据的回顾性分析表明，在睾丸癌患者中，病情越严重，精子发生受损越严重。未发现组织学类型与无精子症和少精子症比例之间存在相关性。与正常人群相比，睾丸癌和非霍奇金淋巴瘤患者的参数更差。在开始挽救生命的癌症治疗之前进行精子冷冻保存，为男性提供了生育子女的最佳机会，应该在化疗前为所有睾丸癌男性提供这种选择，因为细胞毒性疗法可能导致不育。
