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[通过显微密度测定法评估与绝经和卵巢切除术相关的骨质疏松症]

[Evaluation of osteoporosis associated with menopause and oophorectomy by microdensitometry].

作者信息

Ohta H, Nemoto K

机构信息

Department of Obstetrics and Gynecology, Tokyo Electric Power Hospital.

出版信息

Nihon Sanka Fujinka Gakkai Zasshi. 1988 Apr;40(4):415-21.

PMID:3373072
Abstract

Osteoporosis is one of the diseases affecting the elderly that is receiving increasing attention. The present study employed microdensitometry (MD) to evaluate osteoporosis in a relatively younger group of persons aged less than 60. The relationship of this disease to menopause or a history of oophorectomy was also studied. Of 149 cases, this condition was recognized in 33 (22.1%), demonstrating the effectiveness of the MD method. Of 41 premenopausal subjects, osteoporosis was recognized in 8, (19.5%), as compared to 5 of 36 postmenopausal subjects (13.9%), suggesting that the prevalence of this condition was also low in the postmenopausal group and thus suggesting that the menopause was not necessarily a point of importance in the development of this condition. Furthermore the condition was recognized in 20 of 72 cases (27.8%) with a history of total oophorectomy, showing a higher rate than in either the premenopausal or postmenopausal groups. In addition a direct correlation was recognized between the prevalence of osteoporosis and the period since total oophorectomy. These results suggested a strong relationship between total oophorectomy and the occurrence of osteoporosis.

摘要

骨质疏松症是一种影响老年人且日益受到关注的疾病。本研究采用显微密度测定法(MD)对一组相对年轻的、年龄小于60岁的人群进行骨质疏松症评估。还研究了这种疾病与绝经或卵巢切除术史之间的关系。在149例病例中,有33例(22.1%)被诊断为患有这种疾病,证明了MD方法的有效性。在41例绝经前受试者中,有8例(19.5%)被诊断为骨质疏松症,相比之下,36例绝经后受试者中有5例(13.9%),这表明绝经后组中这种疾病的患病率也较低,因此表明绝经不一定是这种疾病发生的重要因素。此外,在72例有全卵巢切除术史的病例中有20例(27.8%)被诊断为患有这种疾病,显示出比绝经前或绝经后组更高的发病率。此外,还发现骨质疏松症的患病率与全卵巢切除术后的时间之间存在直接相关性。这些结果表明全卵巢切除术与骨质疏松症的发生之间存在密切关系。

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