Kim Jaehyun, Lee Gayeong, Chang Woo Sung, Ki Si Hyoung, Park Joo-Cheol
College of Dental Medicine, Columbia University, New York, USA.
Laboratory for the Study of Regenerative Dental Medicine, Department of Oral Histology-Developmental Biology & Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
J Bone Metab. 2021 Feb;28(1):1-10. doi: 10.11005/jbm.2021.28.1.1. Epub 2021 Feb 28.
The bone and dentin have distinct healing processes. The healing process of bones is regenerative, as newly formed tissues are morphologically and functionally similar to the original bone structures. In contrast, the healing process of dentin is reparative due to its failure to replicate some of its key morphological features. In this review, we compare and contrast the healing processes of bone and dentin. We describe how distinct morphological and physiological structures of the 2 tissues translate into different signaling molecules, growth factors, and matrix protein secretion.
骨骼和牙本质具有不同的愈合过程。骨骼的愈合过程是再生性的，因为新形成的组织在形态和功能上与原始骨结构相似。相比之下，牙本质的愈合过程是修复性的，因为它无法复制其一些关键的形态特征。在这篇综述中，我们比较并对比了骨骼和牙本质的愈合过程。我们描述了这两种组织不同的形态和生理结构如何转化为不同的信号分子、生长因子和基质蛋白分泌。
