Cormier L E, Katon W, Russo J, Hollifield M, Hall M L, Vitaliano P P
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle 98195.
J Nerv Ment Dis. 1988 Jun;176(6):351-8. doi: 10.1097/00005053-198806000-00004.
A total of 98 patients with chest pain and no prior history of organic heart disease underwent a structured psychiatric interview at the time of cardiac diagnostic testing, either coronary arteriography or exercise treadmill. Patients with negative cardiac test results were significantly younger and more likely to be female, endorsed a greater number of autonomic symptoms with their chest pain, and were more likely to report atypical chest pain. These patients had significantly higher scores on measures of anxiety and negative life events and significantly greater prevalences of DSM-III panic disorder (47% vs. 6%), major depression (39% vs. 8%), and two or more simple phobias (43% vs. 12%) than did patients with cardiac test results demonstrating coronary artery disease. Using logistic regression, a model was developed to estimate the probability of negative cardiac test results from patient characteristics and psychiatric diagnoses.
共有98名无器质性心脏病病史的胸痛患者在进行心脏诊断检查时，即冠状动脉造影或运动平板试验时，接受了结构化的精神科访谈。心脏检查结果为阴性的患者明显更年轻，女性比例更高，胸痛时伴有更多自主神经症状，且更有可能报告非典型胸痛。与心脏检查结果显示患有冠状动脉疾病的患者相比，这些患者在焦虑和负面生活事件测量中的得分显著更高，且患有DSM-III惊恐障碍（47%对6%）、重度抑郁症（39%对8%）以及两种或更多简单恐惧症（43%对12%）的患病率显著更高。使用逻辑回归分析，建立了一个模型，用于根据患者特征和精神科诊断来估计心脏检查结果为阴性的概率。
