Henneberg Jon, Heidenheim Michael, Munck Lars Kristian
Ugeskr Laeger. 2021 Mar 15;183(11).
This case report describes a patient with colonic Crohn's disease and perianal disease. The patient experienced extensive and severe pyoderma gangrenosum after colectomy. Steroids and anti-inflammatory medication had no effect on pyoderma or the persistent perianal and rectal disease. All pyoderma lesions eventually healed after proctectomy and excision of perianal fistulae. The relevance and effect of surgically induced remission on medically resistant inflammatory bowel disease-associated pyoderma gangrenosum is highlighted.
本病例报告描述了一名患有结肠克罗恩病和肛周疾病的患者。该患者在结肠切除术后出现了广泛且严重的坏疽性脓皮病。类固醇和抗炎药物对坏疽性脓皮病或持续的肛周及直肠疾病均无效果。在直肠切除及肛周瘘管切除术后，所有坏疽性脓皮病病变最终均愈合。强调了手术诱导缓解对药物难治性炎症性肠病相关坏疽性脓皮病的相关性及效果。
