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在健康内皮的眼中,构造性微型 DSAEK 有助于角膜穿孔的闭合。

Tectonic Mini-DSAEK Facilitates Closure of Corneal Perforation in Eyes With Healthy Endothelium.

机构信息

Department of Ophthalmology, Southend University Hospital, Southend, United Kingdom.

Ophthalmology Department, Alexandria University, Alexandria, Egypt; and.

出版信息

Cornea. 2021 Jun 1;40(6):790-793. doi: 10.1097/ICO.0000000000002712.

DOI:10.1097/ICO.0000000000002712
PMID:33734161
Abstract

PURPOSE

The purpose of this study was to report a surgical technique for closure of a traumatic corneal perforation in a patient with healthy endothelium.

METHODS

A 69-year-old male patient presented to Southend University Hospital with a 2.5 mm round temporal corneal perforation caused by a metallic foreign body from an industrial accident. Best-corrected visual acuity at presentation was 6/36. The patient received a tectonic small diameter Descemet stripping automated endothelial keratoplasty (mini-DSAEK) to close the perforation. The patient subsequently developed traumatic cataract and underwent cataract surgery 8 months later. Clinical outcomes at 1 week, 1 month, 3 months, 6 months, and 9 months were evaluated. The primary outcomes of interest were successful sustained closure of the perforation and surgical complications, with secondary outcomes of best-spectacle corrected visual acuity (BSCVA, Snellen) and keratometric astigmatism (KA, Pentacam).

RESULTS

The anterior chamber was reformed by the graft, restoring the globe's mechanical integrity. The bare stroma reepithelized by 1 week. Neither intraoperative nor postoperative surgical complications were reported. The anterior chamber remained deep and formed during subsequent follow-ups through 9 months. At the 9-month follow-up, final best spectacle-corrected visual acuity was 6/6-1 (Snellen fraction). Keratometric astigmatism was 1.1 diopters.

CONCLUSIONS

Tectonic mini-Descemet stripping automated endothelial keratoplasty is a safe technique in the management of corneal perforations too large for tissue adhesives, with a low astigmatic profile and rapid visual recovery.

摘要

目的

本研究旨在报告一种用于健康内皮角膜穿孔的外伤性角膜穿孔的手术技术。

方法

一名 69 岁男性患者因工业事故中的金属异物导致颞侧角膜 2.5 毫米圆形穿孔,到南海岸大学医院就诊。就诊时最佳矫正视力为 6/36。患者接受了组织小型直径 Descemet 剥离自动内皮角膜移植术(mini-DSAEK)以封闭穿孔。患者随后发生外伤性白内障,并在 8 个月后接受白内障手术。在 1 周、1 个月、3 个月、6 个月和 9 个月时评估临床结果。主要观察指标为穿孔持续封闭和手术并发症的成功,次要观察指标为最佳矫正视力(BSCVA,Snellen)和角膜散光(KA,Pentacam)。

结果

移植物重建了前房,恢复了眼球的机械完整性。裸基质在 1 周内重新上皮化。术中或术后均未报告手术并发症。在随后的 9 个月随访中,前房一直保持深且形成。在 9 个月的随访中,最终最佳矫正视力为 6/6-1(Snellen 分数)。角膜散光为 1.1 屈光度。

结论

组织 mini-DSAEK 在处理太大而无法使用组织粘合剂的角膜穿孔时是一种安全的技术,具有低散光和快速视力恢复的特点。

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Cornea. 2021 Jun 1;40(6):790-793. doi: 10.1097/ICO.0000000000002712.
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引用本文的文献

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Sci Rep. 2024 Nov 12;14(1):27675. doi: 10.1038/s41598-024-79376-1.
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DALK combined intralamellar tectonic patch graft: an alternative approach to treat frank corneal perforation.DALK 联合板层间组织补片移植:治疗单纯性角膜穿孔的一种替代方法。
BMC Ophthalmol. 2023 Oct 27;23(1):436. doi: 10.1186/s12886-023-03179-7.
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Patch endothelial keratoplasty for corneal perforations secondary to ocular surface disease: case series.
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Graefes Arch Clin Exp Ophthalmol. 2024 Feb;262(2):519-526. doi: 10.1007/s00417-023-06194-y. Epub 2023 Aug 18.
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BMJ Case Rep. 2022 Apr 22;15(4):e247345. doi: 10.1136/bcr-2021-247345.