Street D L, O'Brien M S, Ricotta J J, Ekholm S E, Ouriel K, Green R M, DeWeese J A
Department of Surgery, University of Rochester School of Medicine and Dentistry, NY.
J Vasc Surg. 1988 Jun;7(6):798-801. doi: 10.1067/mva.1988.avs0070798.
A review was undertaken of all patients seen in our institution between January 1978 and March 1987 in whom a cerebral CT scan was obtained in association with elective carotid endarterectomy. Three hundred fifty-nine such patients were identified. In a subgroup of 89 patients who were neurologically normal after carotid endarterectomy, scans were performed at least 48 hours after surgery to quantitate the incidence of silent postoperative infarction. These scans were interpreted by one neuroradiologist. Preoperative cerebral CT scans showed ipsilateral infarction in 146 of 359 patients (40.6%). Ipsilateral infarction was most common in patients with stroke (76%) but was also seen in 32.8% of patients with transient ischemic attacks, in 9 of 40 patients (22.5%) with nonhemispheric symptoms, and in 9 of 45 patients (20%) with asymptomatic hemodynamically significant carotid stenosis. The postoperative stroke rate was not significantly increased by the presence of infarct on preoperative cerebral CT scan (2.6% vs 1.9%). New infarcts were seen on cerebral CT scanning after carotid endarterectomy in 2 of 89 patients with no detectable neurologic abnormality (2.3%). This study demonstrates a high frequency of ipsilateral infarction in patients having elective carotid endarterectomy, even in those patients with clinical symptom complexes thought by many physicians to be relatively benign (i.e., transient cerebral ischemia, nonhemispheric ischemia, and asymptomatic carotid stenoses).(ABSTRACT TRUNCATED AT 250 WORDS)
我们对1978年1月至1987年3月间在我院接受选择性颈动脉内膜切除术并进行了脑部CT扫描的所有患者进行了回顾性研究。共确定了359例此类患者。在颈动脉内膜切除术后神经功能正常的89例患者亚组中,术后至少48小时进行扫描以量化无症状术后梗死的发生率。这些扫描由一名神经放射科医生解读。术前脑部CT扫描显示,359例患者中有146例(40.6%)存在同侧梗死。同侧梗死在中风患者中最为常见(76%),但在短暂性脑缺血发作患者中也有32.8%出现,在40例有非半球症状的患者中有9例(22.5%)出现,在45例无症状血流动力学显著颈动脉狭窄的患者中有9例(20%)出现。术前脑部CT扫描显示有梗死并不显著增加术后中风发生率(2.6%对1.9%)。在89例无明显神经功能异常的患者中,有2例(2.3%)在颈动脉内膜切除术后脑部CT扫描发现新的梗死。本研究表明,接受选择性颈动脉内膜切除术的患者同侧梗死发生率很高,即使在许多医生认为临床症状相对良性的患者中(即短暂性脑缺血、非半球缺血和无症状颈动脉狭窄)也是如此。(摘要截短于250字)