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摩洛哥首次报告一株严重急性呼吸综合征冠状病毒2（SARS-CoV-2）基因组序列，其刺突蛋白存在His69-Val70缺失及Asn439Lys突变

First Report of a SARS-CoV-2 Genome Sequence with a Spike His69-Val70 Deletion and an Asn439Lys Mutation in Morocco.

作者信息

Aanniz Tarik, Ouadghiri Mouna, Bendahou Mohammed Amine, Chemao-Elfihri Mohammed Walid, Chenaoui Mohamed, Dakka Hanae, Allaoui Afaf, Touzani Otmane, Benaouda Amina, Belefquih Bouchra, Amzazi Saaïd, Belyamani Lahcen, Ibrahimi Azeddine

机构信息

Medical Biotechnology Laboratory, Bioinova Research Center, Rabat Medical and Pharmacy School, Mohammed Vth University, Rabat, Morocco.

Research Center of Plant and Microbial Biotechnologies, Biodiversity, and Environment, Faculty of Sciences, Mohammed Vth University, Rabat, Morocco.

出版信息

Microbiol Resour Announc. 2021 Mar 18;10(11):e00027-21. doi: 10.1128/MRA.00027-21.

DOI:10.1128/MRA.00027-21
PMID:33737349
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7975867/
Abstract

We report the nearly complete genome sequence and the genetic variations of a clinical sample of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) collected from a nasopharyngeal swab specimen from a male patient from Harhoura-Rabat, Morocco. The sequence, which was obtained using Ion Torrent technology, is valuable as it carries a recently described deletion (His69-Val70) and substitution (Asn439Lys).

摘要

我们报告了从摩洛哥拉巴特市哈胡拉的一名男性患者鼻咽拭子样本中采集的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）临床样本的近乎完整的基因组序列及其遗传变异。该序列是使用Ion Torrent技术获得的，它很有价值，因为它带有最近描述的缺失（His69-Val70）和替换（Asn439Lys）。

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