University of Blida, Department of Nephrology, Hospital Establishment Specializing in Organ and Tissue Transplantation (TOT) of Blida, Blida, Algeria.
Department of Anesthesiology, University Hospital Center, Blida, Algeria.
Pan Afr Med J. 2020 Dec 22;37(Suppl 1):51. doi: 10.11604/pamj.supp.2020.37.51.26850. eCollection 2020.
Patients on hemodialysis are a group at risk for infection with SARS-CoV-2 due to impaired immunity. Our knowledge of the specific characteristics of the disease in this population is limited. Our study aims to improve our understanding of diagnostic, therapeutic, and prognostic aspects of this disease. Seventy hemodialysis patients tested by RT-PCR positive for SARS-CoV-2 were hospitalized in the nephrology department from April 1 to September 30, 2020. The patients' average age was 60.3 ± 15.0 years (18 - 88 years); including 39 patients (55.7%) were male. The comorbidities found were hypertension (67.1%), diabetes (32.9%), and obesity (17.1%). Our patients' laboratory abnormalities were leukopenia (15.7%) and lymphopenia in 60% of patients. The pulmonary involvement on computed tomography was classified as moderate (74.3%) and severe in 24.3% of cases. Fifty-seven patients (78.6%) had received hydroxychloroquine and 14 patients (20%) antivirals therapy. We recorded 82.9% of cured patients and 17.1% of deaths in our series. The death occurred 8 ± 7.5 days (1 - 25 days) of hospitalization. Hemodialysis centres are high-risk places, and hemodialysis patients are considered a vulnerable population during the COVID-19 pandemic. They should be given special attention.
血液透析患者由于免疫功能受损，是感染 SARS-CoV-2 的高危人群。我们对该人群疾病的具体特征的了解有限。我们的研究旨在提高对该疾病诊断、治疗和预后方面的认识。2020 年 4 月 1 日至 9 月 30 日，肾内科收治了 70 名经 RT-PCR 检测 SARS-CoV-2 阳性的血液透析患者。患者平均年龄为 60.3 ± 15.0 岁（18-88 岁）；包括 39 名（55.7%）男性。发现的合并症有高血压（67.1%）、糖尿病（32.9%）和肥胖症（17.1%）。我们的患者实验室异常包括白细胞减少（15.7%）和淋巴细胞减少症（60%的患者）。计算机断层扫描的肺部受累情况为中度（74.3%）和重度（24.3%）。57 名患者（78.6%）接受了羟氯喹治疗，14 名患者（20%）接受了抗病毒治疗。在我们的系列研究中，记录了 82.9%的治愈患者和 17.1%的死亡患者。死亡发生在住院后 8 ± 7.5 天（1-25 天）。血液透析中心是高风险场所，血液透析患者在 COVID-19 大流行期间被认为是弱势群体。他们应该得到特别关注。
