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双腔原位心脏移植术后下腔静脉梗阻:病例系列

Obstruction of the inferior vena cava following bicaval orthotopic heart transplantation: a case series.

作者信息

Abudan Anas, Kidd Brent, Hild Peter, Gupta Bhanu

机构信息

Department of Medicine, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd, Kansas City, KS 66160, USA.

Department of Anesthesiology, University of Kansas Medical Center, Kansas City, 3901 Rainbow Blvd, Kansas City, KS 66160, USA.

出版信息

Eur Heart J Case Rep. 2021 Feb 20;5(2):ytab046. doi: 10.1093/ehjcr/ytab046. eCollection 2021 Feb.

DOI:10.1093/ehjcr/ytab046
PMID:33738420
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7954254/
Abstract

BACKGROUND

Inferior vena cava (IVC) obstruction is a rare complication of orthotopic heart transplantation (OHT) and is unique to bicaval surgical technique. The clinical significance, diagnosis, complications, and management of post-operative IVC anastomotic obstruction have not been adequately described.

CASE SUMMARY

Two patients with end-stage heart failure presented for bicaval OHT. Post-operative course was complicated with shock refractory to fluid resuscitation and inotropic/vasopressor support. Obstruction at the IVC-right atrial (RA) anastomosis was diagnosed on transoesophageal echocardiography (TOE), prompting emergent reoperation. In both cases, a large donor Eustachian valve was found to be restricting flow across the IVC-RA anastomosis. Resection of the valve resulted in relief of obstruction across the anastomosis and subsequent improvement in haemodynamics and clinical outcome.

DISCUSSION

Presumably rare, we present two cases of IVC obstruction post-bicaval OHT. Inferior vena cava obstruction is an under-recognized cause of refractory hypotension and shock in the post-operative setting. Prompt recognition using TOE is crucial for immediate surgical correction and prevention of multi-organ failure. Obstruction can be caused by a thickened Eustachian valve caught in the suture line at the IVC anastomosis, which would require surgical resection.

摘要

背景

下腔静脉(IVC)梗阻是原位心脏移植(OHT)的一种罕见并发症,且仅见于双腔静脉手术技术。术后IVC吻合口梗阻的临床意义、诊断、并发症及处理尚未得到充分描述。

病例摘要

两名终末期心力衰竭患者接受了双腔静脉OHT。术后病程出现对液体复苏、强心/血管升压药物支持均无效的休克。经食管超声心动图(TOE)诊断为IVC-右心房(RA)吻合口梗阻,促使紧急再次手术。在两例患者中,均发现一个大的供体下腔静脉瓣限制了IVC-RA吻合口的血流。切除该瓣膜后,吻合口梗阻缓解,血流动力学及临床结局随后得到改善。

讨论

我们报道了两例双腔静脉OHT术后IVC梗阻的病例,推测此类病例较为罕见。下腔静脉梗阻是术后难治性低血压和休克的一个未被充分认识的原因。使用TOE进行快速诊断对于立即进行手术矫正及预防多器官功能衰竭至关重要。梗阻可能由位于IVC吻合口缝线处的增厚的下腔静脉瓣引起,这需要手术切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed19/7954254/bd65d2e8d7e1/ytab046f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed19/7954254/8d67dc078279/ytab046f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed19/7954254/e4a4c1b8cc6a/ytab046f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed19/7954254/bd65d2e8d7e1/ytab046f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed19/7954254/8d67dc078279/ytab046f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed19/7954254/e4a4c1b8cc6a/ytab046f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed19/7954254/bd65d2e8d7e1/ytab046f3.jpg

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本文引用的文献

1
Inferior Vena Cava Stenosis After Bicaval Orthotopic Heart Transplantation.
J Cardiothorac Vasc Anesth. 2019 Sep;33(9):2561-2568. doi: 10.1053/j.jvca.2019.02.021. Epub 2019 Feb 21.
2
A Rare Case of Stenosis at the Inferior Vena Cava to Right Atrium Anastomosis After Bicaval Orthotopic Heart Transplantation.双腔原位心脏移植术后下腔静脉至右心房吻合口狭窄1例罕见病例
Semin Cardiothorac Vasc Anesth. 2019 Dec;23(4):418-421. doi: 10.1177/1089253219832608. Epub 2019 Feb 27.
3
Hybrid treatment of inferior vena cava obstruction after orthotopic heart transplantation.原位心脏移植术后下腔静脉梗阻的综合治疗
Interact Cardiovasc Thorac Surg. 2010 Dec;11(6):817-9. doi: 10.1510/icvts.2010.245415. Epub 2010 Sep 17.
4
Case report: inferior vena-cava right atrial anastomotic stenosis after bicaval orthotopic heart transplantation.病例报告:双腔原位心脏移植术后下腔静脉-右心房吻合口狭窄
Can J Anaesth. 2006 Oct;53(10):1039-43. doi: 10.1007/BF03022534.
5
Orthotopic cardiac transplantation: comparison of outcome using biatrial, bicaval, and total techniques.原位心脏移植:双心房、双腔静脉和全心脏技术的结局比较
J Card Surg. 2005 Jan-Feb;20(1):102-6. doi: 10.1111/j.0886-0440.2005.05011.x.
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Obstruction of the inferior vena cava following total heart lung transplantation: successful treatment by balloon angioplasty.
J Heart Lung Transplant. 2000 May;19(5):488-91. doi: 10.1016/s1053-2498(00)00090-5.