Department of Dermatology, University of California San Diego, San Diego, CA, USA.
Department of Pathology, Rady Children's Hospital, San Diego, CA, USA.
Pediatr Dermatol. 2021 May;38(3):647-651. doi: 10.1111/pde.14569. Epub 2021 Mar 18.
We present a case of a female neonate with a cluster of six skin colored to yellowish pseudovesicular papules on her right forearm present since birth, initially thought to be a herpes simplex virus infection. Punch biopsy with immunostaining revealed a diagnosis of S100-negative, CD163-positive congenital cutaneous non-neural granular cell tumor. Only four other reports are presented in the literature of this entity, three of which also presented on the arm with somewhat similar clinical findings. We briefly reviewed the subtypes of classic and S100-negative non-neural granular cell tumors.
我们报告了一例女性新生儿病例,其右前臂出生时即出现一簇 6 个肤色至淡黄色的假疱疹样丘疹,最初被认为是单纯疱疹病毒感染。皮肤活检免疫组化显示 S100 阴性、CD163 阳性先天性皮肤非神经颗粒细胞瘤的诊断。文献中仅报道了另外 4 例该疾病的病例,其中 3 例也发生在手臂上,临床发现有些相似。我们简要回顾了经典型和 S100 阴性非神经颗粒细胞瘤的亚型。