Hospital of the University of Pennsylvania and Perleman School of Medicine, Philadelphia, PA.
Princeton University, Princeton, NJ.
Pain Physician. 2021 Mar;24(2):E231-E237.
Opioid abuse has been an increasing problem since the 1990s. With over 47,000 opioid related deaths recorded in 2017 alone, concerns have been raised regarding the dangers of introducing opioids perioperatively to patients undergoing major surgeries.
The present study proposes to examine the frequency, amount, and trends in post-operative opioid consumption in patients undergoing orthopedic surgical procedures.
This was a randomized, retrospective questionnaire-based study.
Patients who underwent any type of orthopedic surgery at the University of Pennsylvania Presbyterian Hospital from 1/1/2018 to 3/12/2019 were randomly selected and called during the summer of 2019.
In this retrospective questionnaire-based study, 828 patients were called by telephone in the summer of 2019. These patients were asked a variety of questions involving opioid consumption behavior post-surgery. The study ended after receiving responses from 200 patients.
Nineteen (9.5%) patients reported positively for experiencing euphoria while taking opioids post-surgery. Of the 200 patients contacted, 6 patients (3%) reported switching to marijuana instead of opioids. Thirty-eight (19%) patients preferred to take no opioids at all post-surgery, and one patient was found to have given their prescription to a family member or friend. Twenty-one patients (10.5%) were found to have been taking opioids for non-severe pain. Blacks and whites were the most common racial demographics, making up 84 and 109 of the totals, respectively. The odds ratios for all of the predictors showed that the relative risk for opioid misuse was higher for black patients than white patients (OR = 3.034). There was no relationship between the intra- and post-operative opioid administration and long-term opioid misuse.
Patients are self-selected and had the option to opt out of the study when contacted. Some patients may not have been available to answer the phone when our study was being conducted. This study was only conducted for orthopedic patients and for patients who received surgery at the University of Pennsylvania Presbyterian Hospital, thus affecting the demographics for our research.
Prescription opioid misuse is more common among the black population. The total opioid consumption is frequently lower than the quantity prescribed. Patients frequently use opioids even though they feel that pain is insufficient to deserve such an intervention. Euphoria is experienced by a significant number of patients taking prescription opioids Often patients do not take any opioids, although they had prescriptions.
自 20 世纪 90 年代以来,阿片类药物滥用一直是一个日益严重的问题。仅在 2017 年,就记录了超过 47,000 例与阿片类药物相关的死亡,人们对在接受重大手术的患者围手术期引入阿片类药物的危险表示担忧。
本研究旨在检查接受骨科手术的患者术后阿片类药物使用的频率、数量和趋势。
这是一项随机、回顾性基于问卷的研究。
宾夕法尼亚大学长老会医院 2018 年 1 月 1 日至 2019 年 3 月 12 日期间接受任何类型骨科手术的患者被随机选择,并于 2019 年夏季进行电话呼叫。
在这项回顾性基于问卷的研究中,2019 年夏季通过电话呼叫了 828 名患者。这些患者被问及各种涉及术后阿片类药物消费行为的问题。在收到 200 名患者的回复后,研究结束。
19 名(9.5%)患者报告在术后服用阿片类药物时感到欣快。在 200 名联系的患者中,有 6 名(3%)患者报告改用大麻而不是阿片类药物。38 名(19%)患者术后宁愿完全不服用阿片类药物,一名患者发现将处方给了家庭成员或朋友。21 名(10.5%)患者发现正在服用阿片类药物治疗非严重疼痛。黑人和白人是最常见的种族人群,分别占总数的 84%和 109%。所有预测因素的优势比表明,黑人患者阿片类药物滥用的相对风险高于白人患者(OR=3.034)。术中与术后阿片类药物给药与长期阿片类药物滥用之间没有关系。
患者是自行选择的,当被联系时,他们可以选择退出研究。当我们进行研究时,有些患者可能无法接听电话。本研究仅针对骨科患者和在宾夕法尼亚大学长老会医院接受手术的患者进行,因此影响了我们研究的人口统计学。
阿片类药物处方滥用在黑人群体中更为常见。阿片类药物的总消耗量通常低于规定的数量。尽管患者认为疼痛不足以进行这种干预,但仍经常使用阿片类药物。服用处方阿片类药物的患者中有相当数量的人感到欣快。经常有患者不服用任何阿片类药物,尽管他们有处方。