Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
Mol Cell. 2021 Mar 18;81(6):1126-1127. doi: 10.1016/j.molcel.2021.02.027.
Frattini et al. (2021) demonstrate that TopBP1 forms phase-separated nuclear condensates to promote activation of ATR in cells experiencing genomic stress.
弗拉蒂尼等人（2021 年）证明，TopBP1 形成液-液相分离的核凝聚物，以促进细胞在经历基因组压力时 ATR 的激活。
