Estrem S A, Haghighi S, Levy W J, Wertheimer R, Kendall M
Division of Otolaryngology, Head and Neck Surgery, University of Missouri-Columbia, School of Medicine 65212.
Laryngoscope. 1988 Jun;98(6 Pt 1):628-31. doi: 10.1288/00005537-198806000-00010.
Transcranial brain stimulation by either electrical or noninvasive magnetic stimulation has produced motor responses of limb musculature. However, recordings from muscles innervated by cranial nerves have not previously been reported. A right-sided craniotomy was performed in 18 dogs. An electric stimulus was delivered to the motor cortex via surface electrodes and evoked EMG responses were recorded from the tongue musculature to determine conduction time. Magnetic stimulation of the motor cortex yielded EMG latencies similar to those obtained by electrical direct cortical stimulation, thus demonstrating the potential of magnetic stimulation in intraoperative and outpatient clinical evaluation of hypoglossal nerve disorders. For the first time, it appears possible to noninvasively stimulate the cranial nerves proximal to the point of injury and to evaluate more central conduction pathways.
通过电刺激或无创磁刺激进行的经颅脑刺激已产生肢体肌肉组织的运动反应。然而，此前尚未有关于由颅神经支配的肌肉的记录报告。对18只狗进行了右侧开颅手术。通过表面电极向运动皮层施加电刺激，并从舌肌记录诱发的肌电图反应以确定传导时间。运动皮层的磁刺激产生的肌电图潜伏期与通过直接皮层电刺激获得的潜伏期相似，从而证明了磁刺激在舌下神经疾病的术中及门诊临床评估中的潜力。首次有可能在损伤点近端对颅神经进行无创刺激，并评估更中枢的传导通路。
