Zhang Jinyi, Yi Baozhu, Wang Ledan, Hu Yue
Departments of Obstetrics/Gynecology, The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Lucheng,325000, Zhejiang, China.
Departments of Obstetrics/Gynecology, The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Lucheng,325000, Zhejiang, China.
Eur J Obstet Gynecol Reprod Biol. 2021 May;260:56-58. doi: 10.1016/j.ejogrb.2020.11.022. Epub 2020 Nov 10.
Stress urinary incontinence (SUI), as one of the manifestations of pelvic floor dysfunction diseases with high incidence, seriously affects women's physical and mental health and quality of life. The etiology and pathogenesis of SUI are complex and not yet completely clear, now believed to be involved with environmental factors, genetic factors and cross-cutting factors between the two. SUI genetic susceptibility may be related to single nucleotide polymorphism. This article reviews the current studies on SUI-related single nucleotide polymorphisms.
压力性尿失禁（SUI）作为发病率较高的盆底功能障碍性疾病的表现之一，严重影响女性的身心健康和生活质量。SUI的病因和发病机制复杂，尚未完全明确，目前认为与环境因素、遗传因素以及二者之间的交叉因素有关。SUI的遗传易感性可能与单核苷酸多态性有关。本文综述了目前关于SUI相关单核苷酸多态性的研究。
