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加纳卒中后多维元素补充剂使用的流行情况及其预测因素。

Prevalence and Predictors of Multivitamin Supplement Use After Stroke in Ghana.

机构信息

Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Department of Neurology, University of California, San Francisco, USA.

出版信息

J Stroke Cerebrovasc Dis. 2021 Jun;30(6):105735. doi: 10.1016/j.jstrokecerebrovasdis.2021.105735. Epub 2021 Mar 18.

Abstract

BACKGROUND

Multivitamins are commonly used supplements in high income countries, but their net benefit-risk, remains inconclusive. Little is known about the prevalence and predictors of multivitamin supplementation among individual with chronic illnesses in sub-Saharan Africa, especially stroke.

PURPOSE

To assess the frequency and factors associated with of use of multivitamin supplement among stroke survivors in Ghana.

METHODS

We analyzed prospectively collected data on consecutively encountered stroke survivors seen at an out-patient clinic in Ghana between January 2018 and March 2020. We collected baseline demographic and clinical details, and use of multivitamins among other secondary prevention medications prescribed. We assessed factors associated with multivitamin supplementation using a multivariable logistic regression analysis.

RESULTS

Among 1,101 stroke survivors, 324 (29.4%) were on multivitamin supplements. Factors independently associated with multivitamin use were being divorced (OR 2.88; 95% CI: 1.52-5.47), time since diagnosis of index per each month increase (OR 0.99; 95% CI: 0.99-1.00), and number of prescribed classes of antihypertensive medications (OR 0.81; 95% CI: 0.72-0.92).

CONCLUSION

Nearly a third of stroke survivors in this Ghanaian sample were on multivitamin supplementation, with select socio-clinical factors being linked to this practice. Future studies should examine how/if this practice is interfering with optimal stroke outcomes.

摘要

背景

复合维生素是高收入国家常用的补充剂,但它们的净效益-风险仍不确定。在撒哈拉以南非洲,特别是在中风患者中,关于慢性病患者服用复合维生素补充剂的流行程度和预测因素知之甚少。

目的

评估加纳中风幸存者服用复合维生素补充剂的频率和相关因素。

方法

我们对 2018 年 1 月至 2020 年 3 月期间在加纳门诊连续遇到的中风幸存者前瞻性收集的数据进行了分析。我们收集了基线人口统计学和临床详细信息,以及其他规定的二级预防药物中是否使用复合维生素。我们使用多变量逻辑回归分析评估了与复合维生素补充相关的因素。

结果

在 1101 名中风幸存者中,有 324 名(29.4%)服用复合维生素补充剂。与使用复合维生素相关的独立因素包括离婚(OR 2.88;95%CI:1.52-5.47)、指数诊断后每个月的时间增加(OR 0.99;95%CI:0.99-1.00)和规定的降压药物类别数(OR 0.81;95%CI:0.72-0.92)。

结论

在加纳的这一样本中,近三分之一的中风幸存者服用复合维生素补充剂,某些社会临床因素与这种做法有关。未来的研究应研究这种做法如何/是否会干扰最佳中风结果。

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