International Center for the Assessment of Nutritional Status (ICANS), Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.
Obesity Unit - Laboratory of Nutrition and Obesity Research, Department of Endocrine and Metabolic Diseases, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Obes Facts. 2021;14(2):205-213. doi: 10.1159/000513283. Epub 2021 Mar 19.
The COVID-19 pandemic is spreading all over the world, particularly in developed countries where obesity is also widespread. There is a high frequency of increased BMI in patients admitted to intensive care for SARS-CoV-2 infection with a major severity in patients with an excess of visceral adiposity. Patients at risk of severe SARS-CoV-2 acute respiratory syndrome are characterised by the high prevalence of pre-existing diseases (high blood pressure and cardiovascular disease, diabetes, chronic respiratory disease, or cancer), most of them typically present in severely obese patients. Indeed, the biological role of adipose tissue in sustaining SARS-CoV-2 infection is not completely elucidated.
The forced isolation due to pandemic containment measures abruptly interrupted the rehabilitation programs to which many patients with severe obesity were enrolled. People affected by obesity, and especially those with severe obesity, should continue clinical rehabilitation programs, taking extra measures to avoid COVID-19 infection and reinforcing the adoption of preventive procedures. In this review, the available data on obesity and COVID-19 are discussed along with evidence-based strategies for maintaining the necessary continuous rehabilitation programs. Key Messages: Greater attention is needed for obese and severely obese patients in the face of the current COVID-19 pandemic, which represents a huge challenge for both patients and healthcare professionals. The adoption of new strategies to guarantee adequate and continuous multidisciplinary nutritional rehabilitation programs will be crucial to control the severity of SARS-CoV-2 infection in high-risk populations as well as the worsening of obesity-linked complications. Health authorities should be urged to equip hospitals with tools for the diffusion of telemedicine to maintain physician-patient communication, which is fundamental in chronic and complicated obese patients.
COVID-19 疫情在全球范围内蔓延,尤其在肥胖症也普遍存在的发达国家。因 SARS-CoV-2 感染而住进重症监护病房的患者中,BMI 增加的频率较高,内脏脂肪过多的患者病情更为严重。有发生严重 SARS-CoV-2 急性呼吸综合征风险的患者,其特征是患有多种先前存在的疾病(高血压和心血管疾病、糖尿病、慢性呼吸道疾病或癌症),其中大多数患者通常为严重肥胖患者。事实上,脂肪组织在维持 SARS-CoV-2 感染方面的生物学作用尚未完全阐明。
由于大流行遏制措施而导致的强制隔离,突然中断了许多严重肥胖患者参加的康复计划。肥胖症患者,尤其是那些患有严重肥胖症的患者,应继续进行临床康复计划,采取额外措施避免 COVID-19 感染,并加强预防措施的实施。在这篇综述中,讨论了肥胖症和 COVID-19 的现有数据,以及维持必要的连续康复计划的循证策略。
在当前 COVID-19 大流行面前,肥胖症和严重肥胖症患者需要得到更多关注,这对患者和医疗保健专业人员都是巨大的挑战。为了控制高危人群中 SARS-CoV-2 感染的严重程度以及肥胖相关并发症的恶化,需要采取新策略来保证充分和持续的多学科营养康复计划。应敦促卫生当局为医院配备远程医疗工具,以维持医患沟通,这对慢性和复杂肥胖患者至关重要。