Division of Nephrology, Tufts Medical Center, Boston, Massachusetts, USA.
Division of Nephrology, Tufts Medical Center, Boston, Massachusetts, USA.
Kidney Int. 2021 Apr;99(4):808-811. doi: 10.1016/j.kint.2020.12.032.
For application to general populations, estimating equations for glomerular filtration rate should be developed and validated in diverse populations, including a wide range of age, race-ethnicity, and clinical conditions. This issue includes reports on the development of new equations by 2 research groups to improve glomerular filtration rate estimation in children and young adults. Both equations performed better than guideline-recommended equations, but both require further evaluation of generalizability, and neither fulfills the goal of development in a diverse population.
对于一般人群的应用，应该在包括广泛年龄、种族和临床条件的不同人群中开发和验证肾小球滤过率的估算方程。本议题包括 2 个研究小组关于开发新方程以改善儿童和青年成年人肾小球滤过率估算的报告。这两个方程的表现均优于指南推荐的方程，但两者都需要进一步评估其普遍性，且都没有达到在不同人群中开发的目标。
