Zemła B, Zielonka I, Kołosza Z
Institute of Oncology, Gliwice, Poland.
Neoplasma. 1988;35(2):135-43.
A case-control study has been applied to analyze lung cancer risk, isolating four histopathological groups: differentiated forms of cancer (most often carcinoma planoepitheliale and adenocarcinoma), undifferentiated carcinomas (mainly carcinoma microcellulare and solidum), cancers histologically undeterminated (carcinoma) and cancers not verified histologically, but confirmes radiologically and clinically. 210 patients have been compared with the group of 420 men not suffering from any form of cancer. The results of the undertaken attempt to evaluate lung cancers in relation to certain etiological factors (conditions in the microenvironment of the place of work and tobacco smoking) showed that the influence of tobacco smoking (independently of the kind of tobacco and the form of smoking) on lung cancer incidence was more and more firmly established, and the frequency of incidence increased with the length of the period of smoking. Tobacco smokers and those simultaneously exposed to various dusts and dusts with gases in their microenvironment of the place of work were characterized by higher lung cancer risk (in fact independently on the histological form of the neoplasms), as compared to nonsmokers and those never exposed to air pollution.
一项病例对照研究已被用于分析肺癌风险,将其分为四个组织病理学组:分化型癌症(最常见的是扁平上皮癌和腺癌)、未分化癌(主要是小细胞癌和实体癌)、组织学上未确定的癌症(癌)以及组织学上未证实但经放射学和临床证实的癌症。210名患者与420名未患任何形式癌症的男性组成的组进行了比较。关于某些病因因素(工作场所微环境条件和吸烟情况)评估肺癌的尝试结果表明,吸烟(与烟草种类和吸烟形式无关)对肺癌发病率的影响越来越得到确证,且发病率随吸烟时长增加而上升。与不吸烟者和从未接触过空气污染的人相比,吸烟者以及那些在工作场所微环境中同时接触各种粉尘和含气体粉尘的人患肺癌的风险更高(实际上与肿瘤的组织学形式无关)。