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对自体胆固醇半琥珀酸酯处理的肿瘤细胞、二硝基氯苯和纯化蛋白衍生物进行皮肤试验及其与恶性黑色素瘤患者预后的关系。

Skin tests with autologous cholesteryl hemisuccinate-treated tumor cells, DNCB and PPD and their relationship to prognosis in malignant melanoma patients.

作者信息

Munzarová M, Mechl Z, Kovarík J, Kolcová V

机构信息

Research Institute of Clinical and Experimental Oncology, Brno, Czechoslovakia.

出版信息

Neoplasma. 1988;35(2):229-34.

PMID:3374711
Abstract

Skin tests with autologous cholesteryl hemisuccinate-treated tumor cells were performed in Stage II malignant melanoma patients. In the majority of cases an evident reaction having features of delayed type hypersensitivity was noted. No significant correlation between this reactivity and subsequent course of the disease was found. The same was true for the results of DNCB and PPD skin testing. An analysis of the results of all three tests in the same patient revealed no prognostic significance of this score either.

摘要

对II期恶性黑色素瘤患者进行了自体胆固醇半琥珀酸酯处理的肿瘤细胞皮肤试验。在大多数病例中,观察到具有迟发型超敏反应特征的明显反应。未发现这种反应性与疾病的后续病程之间存在显著相关性。二硝基氯苯(DNCB)和结核菌素纯蛋白衍生物(PPD)皮肤试验结果也是如此。对同一患者的所有三项试验结果进行分析,也未发现该评分具有预后意义。

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Skin tests with autologous cholesteryl hemisuccinate-treated tumor cells, DNCB and PPD and their relationship to prognosis in malignant melanoma patients.对自体胆固醇半琥珀酸酯处理的肿瘤细胞、二硝基氯苯和纯化蛋白衍生物进行皮肤试验及其与恶性黑色素瘤患者预后的关系。
Neoplasma. 1988;35(2):229-34.
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