Okuno T, Moriwaki H, Miyamoto K, Terada T, Nishiguchi T, Itakura T, Hayashi S, Komai N
Department of Neurological Surgery, Hidaka General Hospital, Wakayama, Japan.
No Shinkei Geka. 1988 Mar;16(3):249-57.
We report the usefulness of computed cerebral angiotomography (CT angiography) for demonstrating cerebral aneurysm and the clinical significance of CT angiography for ruptured cerebral aneurysm. Our modified method of CT angiography was easy and less time-consuming. Fifteen seconds after starting a single bolus injection, 1 ml/kg/25 seconds via cubital vein, of contrast medium (60% urograffin), 5 serial 5 mm thick-CT slices were scanned in every 6.5 seconds including 2 seconds of interval, beginning from an axial level 20 mm above the orbitomeatal line and ending at a level 40 mm. A total of 103 patients were examined in this report, consisting of 70 unruptured asymptomatic, 8 unruptured symptomatic (oculomotor nerve palsy) and 25 subarachnoid hemorrhage (SAH). Seven unruptured aneurysms in 4 asymptomatic cases, 2 unruptured aneurysms in 2 symptomatic cases 27 aneurysms in 24 SAH cases were suspected by CT angiography. Of these 36 aneurysms suspected by CT angiography 32 aneurysms were confirmed by cerebral angiography. The detection rate of CT angiography in this report was 89%, higher than those of previous reports. Thirteen aneurysms were located at internal carotid-posterior communicating artery (ICPC) junction. 11 at anterior communicating artery (Acom), 7 at middle cerebral artery (MCA). CT angiography showed a false positive findings in 4 cases, which were all located at Acom. Four aneurysms were not detected in CT angiography, which were all located at MCA and were very small (2-3 mm) in diameter. There were no deteriorated cases during and after CT angiography. We suggest that CT angiography is a useful and safe method for predicting the location of not only unruptured but ruptured aneurysms.
我们报告了计算机脑动脉造影(CT血管造影)在显示脑动脉瘤方面的实用性以及CT血管造影对破裂脑动脉瘤的临床意义。我们改良的CT血管造影方法简便且耗时较少。经肘静脉以1ml/kg/25秒的速度单次推注造影剂(60%泛影葡胺)后15秒,从眶耳线以上20mm的轴位层面开始,每隔6.5秒(包括2秒间隔)扫描5层连续的5mm厚CT切片,直至40mm层面。本报告共检查了103例患者,包括70例未破裂无症状患者、8例未破裂有症状(动眼神经麻痹)患者和25例蛛网膜下腔出血(SAH)患者。CT血管造影怀疑4例无症状患者中有7个未破裂动脉瘤,2例有症状患者中有2个未破裂动脉瘤,24例SAH患者中有27个动脉瘤。在CT血管造影怀疑的这36个动脉瘤中,32个经脑血管造影证实。本报告中CT血管造影的检出率为89%,高于以往报告。13个动脉瘤位于颈内动脉-后交通动脉(ICPC)交界处,11个位于前交通动脉(Acom),7个位于大脑中动脉(MCA)。CT血管造影有4例假阳性结果,均位于Acom。CT血管造影未检测出4个动脉瘤,均位于MCA且直径非常小(2 - 3mm)。CT血管造影期间及之后均无病情恶化病例。我们认为CT血管造影是一种预测未破裂及破裂动脉瘤位置的有用且安全的方法。