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尼泊尔加德满都已证实的山蝰蛇咬伤记录及其分布范围:对亚洲蝰蛇咬伤预防与控制的启示

Documentation of a proven Mountain Pitviper () envenomation in Kathmandu, Nepal, with its distribution ranges: implications for prevention and control of pitviper bites in Asia.

作者信息

Pandey Deb Prasad, Chaudhary Budhan, Ram Shrestha Bhola

机构信息

School of Medicine and Public Health, Faculty of Health and Medicine, The University of Newcastle, Australia.

Department of Veterinary Microbiology and Parasitology, Agriculture and Forestry University, Rampur, Chitwan, Nepal.

出版信息

J Venom Res. 2021 Jan 6;11:1-6. eCollection 2021.

PMID:33747433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7970453/
Abstract

We document inadequately diagnosed coagulopathy (potential to be life threatening) due to bite. Although its bites are common in the hills of Nepal, associated envenomations have not been documented elaborately. Herein, we present the clinical and treatment details of a proven bite and areas where it may pose the risk of envenomations (suggesting huge populations in Asia to be vulnerable to its bites). Its envenomation was managed symptomatically with several non-evidence-based interventions. Since no specific pitviper antivenom is available in Nepal yet, managing coagulopathy associated to envenomation is still challenging. This case emphasizes the need of developing the standard protocol for the diagnosis and management of pitviper bites and study of effectiveness of the available pitviper antivenoms until specific pitviper antivenom is available. Further, the demonstrated distribution localities of this species may have implications for snakebite prevention and designing and distribution of the effective antivenoms.

摘要

我们记录了因[蛇名]咬伤导致的诊断不充分的凝血病(可能危及生命)。尽管其咬伤在尼泊尔山区很常见,但相关的蛇毒中毒情况尚未得到详细记录。在此,我们介绍一例经证实的[蛇名]咬伤的临床和治疗细节,以及它可能造成蛇毒中毒风险的区域(这表明亚洲有大量人口易受其咬伤)。其蛇毒中毒通过几种非循证干预措施进行了对症处理。由于尼泊尔目前尚无特定的蝰蛇抗蛇毒血清,处理与[蛇名]蛇毒中毒相关的凝血病仍然具有挑战性。该病例强调了制定蝰蛇咬伤诊断和管理标准方案以及研究现有蝰蛇抗蛇毒血清有效性的必要性,直到有特定的蝰蛇抗蛇毒血清可用。此外,该物种已证实的分布地点可能对蛇咬伤预防以及有效抗蛇毒血清的设计和分发具有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e398/7970453/3ef09a4ce368/JVR-11-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e398/7970453/7a3b4280c5ad/JVR-11-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e398/7970453/3ef09a4ce368/JVR-11-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e398/7970453/7a3b4280c5ad/JVR-11-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e398/7970453/3ef09a4ce368/JVR-11-1-g002.jpg

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Hematotoxic Manifestations and Management of Green Pit Viper Bites in Thailand.泰国竹叶青蛇咬伤的血液毒性表现及处理
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Do Antibiotics Potentiate Proteases in Hemotoxic Snake Venoms?抗生素是否会增强血液毒素蛇毒中的蛋白酶?
分析 2010-2022 年期间尼泊尔新闻媒体报道的蛇咬伤中毒情况。
PLoS Negl Trop Dis. 2023 Aug 28;17(8):e0011572. doi: 10.1371/journal.pntd.0011572. eCollection 2023 Aug.
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Case Report: Management of an Uncommon Crotaline Snakebite (Ovophis makazayazaya).病例报告:罕见的蝰蛇咬伤(山烙铁头蛇)的处理
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