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墨西哥患者中 COVID-19 的皮肤表现:病例系列及文献综述

Cutaneous manifestations of COVID-19 in Mexican patients: A case series and review of literature.

作者信息

Palomo-Pérez Juan Carlos, Vega-Memije Maria Elisa, Aguilar-Blancas David, González-Martínez Erik, Rangel-Gamboa Lucia

机构信息

External Consultation Division, General Hospital Dr. Manuel Gea González, Ciudad de México, México.

Tláhuac General Hospital, Ciudad de México, México.

出版信息

SAGE Open Med Case Rep. 2021 Feb 23;9:2050313X21997194. doi: 10.1177/2050313X21997194. eCollection 2021.

DOI:10.1177/2050313X21997194
PMID:33747514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7905726/
Abstract

China officially recognized atypical pneumonia outbreak in December 2019; on 11 March 2020, the World Health Organization declared COVID-19 as a pandemic that is produced by a new coronavirus, named SARS-CoV-2, of rapid transmissibility, which can be asymptomatic, with mild to severe respiratory symptoms, and with cardiovascular, neurological, gastrointestinal, and cutaneous complications. Considering that the pandemic prolonged more than initially expected was prognostic, it is essential for the medical community to identify the signs and symptoms of COVID-19. Thus, this work's objectives were to present cases of cutaneous lesions observed in COVID-19 Mexican patients. We register cutaneous lesions in COVID-19 patients referred from internal medicine and otorhinolaryngology services to dermatology. We presented four interesting cases with cutaneous lesions, including exanthema morbilliform, urticaria, chilblains, ecchymosis, and facial edema, and review the available literature. The most frequent cutaneous markers are rash, chilblains, and urticaria. Skin lesions may be the first manifestation of COVID-19, accompany initial respiratory symptoms, or appear during the disease course. Symptoms associated with vascular changes (livedo reticularis and vasculitis) are considered of poor prognosis.

摘要

中国于2019年12月正式确认出现非典型肺炎疫情;2020年3月11日,世界卫生组织宣布新型冠状病毒肺炎为大流行病,该疾病由一种名为严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的新型冠状病毒引起,具有快速传播性,可能无症状,也可能伴有从轻到重的呼吸道症状,以及心血管、神经、胃肠和皮肤并发症。鉴于这场大流行持续的时间比最初预期的更长,对医学界来说,识别新型冠状病毒肺炎的体征和症状至关重要。因此,这项工作的目的是展示在墨西哥新型冠状病毒肺炎患者中观察到的皮肤病变病例。我们记录了从内科和耳鼻喉科转诊至皮肤科的新型冠状病毒肺炎患者的皮肤病变情况。我们展示了4例伴有皮肤病变的有趣病例,包括麻疹样皮疹、荨麻疹、冻疮、瘀斑和面部水肿,并对现有文献进行了综述。最常见的皮肤表现是皮疹、冻疮和荨麻疹。皮肤病变可能是新型冠状病毒肺炎的首发表现,也可能伴随初始呼吸道症状出现,或在病程中出现。与血管变化相关的症状(网状青斑和血管炎)被认为预后较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e77/7905726/94d7e893a379/10.1177_2050313X21997194-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e77/7905726/926e2faa324b/10.1177_2050313X21997194-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e77/7905726/94d7e893a379/10.1177_2050313X21997194-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e77/7905726/926e2faa324b/10.1177_2050313X21997194-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e77/7905726/94d7e893a379/10.1177_2050313X21997194-fig2.jpg

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本文引用的文献

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Management of urticaria in COVID-19 patients: A systematic review.COVID-19 患者荨麻疹的管理:系统评价。
Dermatol Ther. 2021 Jan;34(1):e14328. doi: 10.1111/dth.14328. Epub 2020 Oct 9.
2
Dermatological findings in COVID-19 patients: Mexican experience.新冠病毒肺炎患者的皮肤表现:墨西哥的经验
Int J Dermatol. 2020 Jul;59(7):872-873. doi: 10.1111/ijd.14958. Epub 2020 May 24.
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COVID-19 and Multiorgan Response.新型冠状病毒肺炎与多器官反应
Curr Probl Cardiol. 2020 Aug;45(8):100618. doi: 10.1016/j.cpcardiol.2020.100618. Epub 2020 Apr 28.
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Chilblains in children in the setting of COVID-19 pandemic.新冠疫情背景下儿童的冻疮
Pediatr Dermatol. 2020 May;37(3):406-411. doi: 10.1111/pde.14215. Epub 2020 May 22.
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Erythema multiforme-like eruption in patients with COVID-19 infection: clinical and histological findings.新型冠状病毒肺炎感染患者的多形红斑样皮疹:临床和组织学表现
Clin Exp Dermatol. 2020 Oct;45(7):892-895. doi: 10.1111/ced.14281. Epub 2020 Jun 25.
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Clinical and histological characterization of vesicular COVID-19 rashes: a prospective study in a tertiary care hospital.对水疱型 COVID-19 皮疹的临床和组织学特征分析:在一家三级医院的前瞻性研究。
Clin Exp Dermatol. 2020 Oct;45(7):872-875. doi: 10.1111/ced.14277. Epub 2020 Jun 22.
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J Dermatol Sci. 2020 May;98(2):75-81. doi: 10.1016/j.jdermsci.2020.04.011. Epub 2020 Apr 29.
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Acute Cor Pulmonale in Critically Ill Patients with Covid-19.新型冠状病毒肺炎危重症患者的急性肺源性心脏病
N Engl J Med. 2020 May 21;382(21):e70. doi: 10.1056/NEJMc2010459. Epub 2020 May 6.
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