Theodorou Christina M, Coleman Lauren E, Mateev Stephanie N, Signoff Jessica K, Salcedo Edgardo S
University of California Davis Medical Center, Department of Surgery, USA.
University of California Davis Medical Center, Division of Pediatric Critical Care, USA.
J Pediatr Surg Case Rep. 2021 Apr;67. doi: 10.1016/j.epsc.2021.101812. Epub 2021 Feb 11.
Extracorporeal Life Support (ECLS) is rarely used in pediatric trauma patients due to bleeding risk, and the use of ECLS following angioembolization of traumatic hemorrhage has never been reported in a child. We report a case of a 10-year-old boy run over by a parade float resulting in severe thoracic, abdominal, and pelvic trauma, with hemorrhage from pelvic fractures requiring massive transfusion. Due to ongoing blood product requirements and contrast extravasation near the symphysis pubis, angioembolization of the internal iliac arteries was performed. Extreme hypoxemia persisted despite maximal ventilator support due to pulmonary contusions and aspiration pneumonitis. Six hours after angioembolization, venovenous ECLS was initiated. Following an initial heparin bolus, ECLS was run without anticoagulation for 12 h, but development of circuit clot required resumption of low-dose heparin. After four days, his respiratory status improved substantially and ECLS was discontinued. There were no hemorrhagic complications. The patient was discharged home in good health following inpatient rehabilitation. In this case, ECLS was successfully used in the treatment of post-traumatic respiratory failure 6 h following angioembolization of pelvic hemorrhage in a pediatric trauma patient. Further research is needed to determine the safest interval between hemorrhage control and ECLS in severely injured children.
由于出血风险,体外生命支持(ECLS)在儿科创伤患者中很少使用,且儿童创伤性出血经血管栓塞术后使用ECLS的情况此前从未有过报道。我们报告了一例10岁男孩被游行花车碾压,导致严重的胸部、腹部和骨盆创伤,骨盆骨折出血需要大量输血。由于持续需要血液制品以及耻骨联合附近造影剂外渗,对双侧髂内动脉进行了血管栓塞术。由于肺挫伤和吸入性肺炎,尽管给予了最大程度的呼吸机支持,患者仍持续存在极度低氧血症。血管栓塞术后6小时,启动了静脉-静脉ECLS。在给予初始肝素推注后,ECLS在无抗凝情况下运行了12小时,但出现了回路凝血,需要恢复低剂量肝素治疗。四天后,他的呼吸状况显著改善,ECLS被停用。未出现出血并发症。经过住院康复治疗,患者健康出院。在本病例中,ECLS成功用于一名儿科创伤患者骨盆出血血管栓塞术后6小时的创伤后呼吸衰竭治疗。需要进一步研究以确定严重受伤儿童出血控制与ECLS之间最安全的间隔时间。