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病例报告:一名接受腹膜透析的幼儿反复发生腹膜炎及透析失败

Case Report: Recurring Peritonitis and Dialysis Failure in a Toddler on Peritoneal Dialysis.

作者信息

Mohammed Enas H, Chandy Sajimol, Kadhi Abderrahman E, Shatat Ibrahim F

机构信息

Pediatric Nephrology and Hypertension, Sidra Medicine, Doha, Qatar.

Pediatric Urology, Sidra Medicine, Doha, Qatar.

出版信息

Front Pediatr. 2021 Mar 4;9:632915. doi: 10.3389/fped.2021.632915. eCollection 2021.

Abstract

We report a case of a 2-year-old-boy with end stage renal disease (ESRD) secondary to posterior urethral valves (PUV) on peritoneal dialysis (PD). Our patient developed multiple episodes of peritonitis, refractory anemia and feeding intolerance over a 12-month-period. He was treated with multiple courses of intraperitoneal antibiotics. Despite being on high-calorie formula, he was slowly thriving. The feeding intolerance was attributed to past history of prematurity, gastro-esophageal reflux disease and ESRD co-morbidities. He had anemia resistant to erythrocyte stimulating agents and iron supplementation. His family received re-training and mastered the PD techniques. They reported no breach of the aseptic techniques. His workup which included multiple AP abdominal XR-plain films were read as unremarkable and showed the gastrostomy tube (GT) and the PD catheter in good position. He completed his antibiotic courses as prescribed after each peritonitis episode, peritoneal fluid cultures repeated after each treatment completion showed no growth. During the last peritonitis episode, our patient developed ultrafiltration failure. A cross-table abdominal XR was obtained to evaluate the peritoneal catheter position and showed an intra-abdominal foreign body. During surgery, a needle was laparoscopically removed from the ileum and the PD catheter was replaced. Subsequently, our patient's feeding intolerance and resistant anemia resolved. Finally PD was successfully resumed.

摘要

我们报告一例2岁男孩,因后尿道瓣膜(PUV)继发终末期肾病(ESRD),正在接受腹膜透析(PD)治疗。在12个月的时间里,我们的患者出现了多次腹膜炎、难治性贫血和喂养不耐受。他接受了多疗程的腹腔内抗生素治疗。尽管使用了高热量配方奶,但他的生长发育仍很缓慢。喂养不耐受归因于早产史、胃食管反流病和ESRD合并症。他对红细胞刺激剂和铁剂补充治疗的贫血具有抵抗性。他的家人接受了再培训并掌握了PD技术。他们报告没有违反无菌技术。他的检查包括多次腹部前后位X线平片,结果显示无异常,胃造瘘管(GT)和PD导管位置良好。每次腹膜炎发作后,他都按规定完成了抗生素疗程,每次治疗完成后重复进行的腹膜液培养均未生长。在最后一次腹膜炎发作期间,我们的患者出现了超滤失败。进行了交叉位腹部X线检查以评估腹膜导管位置,结果显示腹腔内有异物。手术中,通过腹腔镜从回肠取出一根针,并更换了PD导管。随后,我们患者的喂养不耐受和难治性贫血得到缓解。最后,PD成功恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4ea/7969517/82e7a5bf7e2e/fped-09-632915-g0001.jpg

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