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本文引用的文献

1
Role of Chronic Suprapubic Tube in the Management of Radiation Induced Urethral Strictures.
Urol Pract. 2017 Nov;4(6):479-485. doi: 10.1016/j.urpr.2016.10.004. Epub 2016 Nov 1.
2
A multi-institutional critical assessment of dorsal onlay urethroplasty for post-radiation urethral stenosis.多机构对放射性后尿道狭窄行背侧加层尿道成形术的关键性评估。
World J Urol. 2021 Jul;39(7):2669-2675. doi: 10.1007/s00345-020-03446-y. Epub 2020 Sep 17.
3
Buccal mucosal graft urethroplasty for radiation-induced urethral strictures: an evaluation using the extended Urethral Stricture Surgery Patient-Reported Outcome Measure (USS PROM).颊黏膜移植尿道成形术治疗放射性尿道狭窄：采用扩展的尿道狭窄手术患者报告结局测量（USS PROM）进行评估。
World J Urol. 2020 Nov;38(11):2863-2872. doi: 10.1007/s00345-020-03102-5. Epub 2020 Feb 18.
4
Histologic characterization of the post-radiation urethral stenosis in men treated for prostate cancer.放射性治疗后前列腺癌患者尿道狭窄的组织学特征。
World J Urol. 2020 Sep;38(9):2269-2277. doi: 10.1007/s00345-019-03031-y. Epub 2019 Nov 30.
5
Prostate cancer radiation and urethral strictures: a systematic review and meta-analysis.前列腺癌放疗与尿道狭窄：系统评价与荟萃分析。
Prostate Cancer Prostatic Dis. 2018 Jun;21(2):168-174. doi: 10.1038/s41391-017-0028-3. Epub 2018 Jan 2.
6
Incidence of Stress Urinary Incontinence After Posterior Urethroplasty for Radiation-induced Urethral Strictures.放射性尿道狭窄行后尿道成形术后压力性尿失禁的发生率
Urology. 2018 Apr;114:188-192. doi: 10.1016/j.urology.2017.11.024. Epub 2017 Nov 27.
7
Management of Urethral Stricture and Bladder Neck Contracture Following Primary and Salvage Treatment of Prostate Cancer.前列腺癌初次及挽救性治疗后尿道狭窄和膀胱颈挛缩的管理
Curr Urol Rep. 2017 Oct;18(10):76. doi: 10.1007/s11934-017-0729-0.
8
ASCENDE-RT: An Analysis of Treatment-Related Morbidity for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost with a Dose-Escalated External Beam Boost for High- and Intermediate-Risk Prostate Cancer.ASCENDE-RT：一项随机试验的治疗相关发病率分析，该试验比较了低剂量率近距离放疗增敏与剂量递增外照射增敏用于高危和中危前列腺癌的情况。
Int J Radiat Oncol Biol Phys. 2017 Jun 1;98(2):286-295. doi: 10.1016/j.ijrobp.2017.01.008. Epub 2017 Jan 6.
9
Treatment of Radiation-Induced Urethral Strictures.放射性尿道狭窄的治疗
Urol Clin North Am. 2017 Feb;44(1):87-92. doi: 10.1016/j.ucl.2016.08.005.
10
Urethral Strictures and Stenoses Caused by Prostate Therapy.前列腺治疗导致的尿道狭窄和缩窄
Rev Urol. 2016;18(2):90-102. doi: 10.3909/riu0685.

放射性所致膜部尿道狭窄的当前治疗方法

Current Management of Membranous Urethral Strictures Due to Radiation.

作者信息

Waterloos Marjan, Martins Francisco, Verla Wesley, Kluth Luis Alex, Lumen Nicolaas

机构信息

Department of Urology, AZ Maria Middelares Ghent, Ghent, Belgium.

Department of Urology, University Hospital Ghent, Ghent, Belgium.

出版信息

Front Surg. 2021 Mar 4;8:635060. doi: 10.3389/fsurg.2021.635060. eCollection 2021.

DOI:10.3389/fsurg.2021.635060
PMID:33748181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7969877/
Abstract

Radiotherapy is a frequently used treatment for prostate cancer. It does not only causes the intended damage to cancer cells, but also affects healthy surrounding tissue. As a result radiation-induced urethral strictures occur in 2.2% of prostate cancer patients. Management of urethral strictures is challenging due to the presence of poor vascularized tissue for reconstruction and the proximity of the sphincter, which can impair the functional outcome. This review provides a literature overview of risk factors, diagnostics and management of radiation-induced urethral strictures.

摘要

放射疗法是前列腺癌常用的治疗方法。它不仅会对癌细胞造成预期的损伤，还会影响周围的健康组织。因此，2.2%的前列腺癌患者会出现放射性尿道狭窄。由于用于重建的组织血管化程度差以及括约肌距离近，这可能会损害功能结果，尿道狭窄的处理具有挑战性。本综述提供了放射性尿道狭窄的危险因素、诊断和处理的文献概述。