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放射性所致膜部尿道狭窄的当前治疗方法

Current Management of Membranous Urethral Strictures Due to Radiation.

作者信息

Waterloos Marjan, Martins Francisco, Verla Wesley, Kluth Luis Alex, Lumen Nicolaas

机构信息

Department of Urology, AZ Maria Middelares Ghent, Ghent, Belgium.

Department of Urology, University Hospital Ghent, Ghent, Belgium.

出版信息

Front Surg. 2021 Mar 4;8:635060. doi: 10.3389/fsurg.2021.635060. eCollection 2021.

DOI:10.3389/fsurg.2021.635060
PMID:33748181
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7969877/
Abstract

Radiotherapy is a frequently used treatment for prostate cancer. It does not only causes the intended damage to cancer cells, but also affects healthy surrounding tissue. As a result radiation-induced urethral strictures occur in 2.2% of prostate cancer patients. Management of urethral strictures is challenging due to the presence of poor vascularized tissue for reconstruction and the proximity of the sphincter, which can impair the functional outcome. This review provides a literature overview of risk factors, diagnostics and management of radiation-induced urethral strictures.

摘要

放射疗法是前列腺癌常用的治疗方法。它不仅会对癌细胞造成预期的损伤，还会影响周围的健康组织。因此，2.2%的前列腺癌患者会出现放射性尿道狭窄。由于用于重建的组织血管化程度差以及括约肌距离近，这可能会损害功能结果，尿道狭窄的处理具有挑战性。本综述提供了放射性尿道狭窄的危险因素、诊断和处理的文献概述。

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本文引用的文献

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