Appelman Z, Blumberg B D, Golabi M, Golbus M S
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California Medical Center, San Francisco.
Obstet Gynecol. 1988 Jun;71(6 Pt 2):1005-8.
Nonimmune hydrops fetalis may be associated with an elevated amniotic fluid delta OD450. Cases of I-cell disease (mucolipidosis II), lethal multiple pterygium syndrome, and alpha-thalassemia are presented, each associated with nonimmune hydrops fetalis and an elevated delta OD450. An elevated delta OD450 does not always indicate isoimmunization, and may be due to increased red blood cell turnover for a variety of reasons associated with nonimmune hydrops fetalis.
非免疫性胎儿水肿可能与羊水ΔOD450升高有关。本文介绍了I细胞病(黏脂贮积症II型)、致死性多发性翼状胬肉综合征和α地中海贫血的病例,每例均与非免疫性胎儿水肿及ΔOD450升高有关。ΔOD450升高并不总是提示同种免疫,可能是由于与非免疫性胎儿水肿相关的多种原因导致红细胞周转率增加所致。