肺栓塞溶栓治疗是否降低慢性并发症风险？

Does thrombolysis for pulmonary embolism reduce the risk of chronic complications?

机构信息

Internal Medicine, University Hospital Lewisham Lewisham and Greenwich National Health Service Trust, London.

Acute Internal Medicine, East Surrey Hospital, Surrey and Sussex Healthcare National Health Service Trust, Redhill.

出版信息

Acute Med. 2021;20(1):15-17.

Abstract

We assessed the efficacy of thrombolysis in avoiding long-term complications. Notes of patients thrombolysed for PE in the 2-year period were reviewed. The initial CTPA and echocardiogram results before thrombolysis were compared to the results of follow up imaging repeated after 6 months. Twenty-two patients were thrombolysed for PE. 14 patients had sub-massive PE and 8 patients had massive PE. The right ventricle (RV) was dilated on pre-thrombolysis echocardiogram in 16 patients. On follow up echocardiography all patients with massive PE (6 studies) had a normal RV size, with pulmonary artery pressures (PAP) of 29mmHg. Follow up echocardiography of patients with submassive PE (13 studies) showed 11 patients with a normal RV, with PAP of 28 mmHg.

摘要

我们评估了溶栓治疗避免长期并发症的效果。回顾了在 2 年期间接受 PE 溶栓治疗的患者的病历。将溶栓治疗前的初始 CTPA 和超声心动图结果与 6 个月后重复的随访影像结果进行比较。对 22 名患者进行了 PE 溶栓治疗。14 名患者为次大面积 PE，8 名患者为大面积 PE。16 名患者溶栓前的超声心动图显示右心室（RV）扩张。在 6 项研究中，所有患有大面积 PE 的患者在后续超声心动图检查中 RV 大小正常，肺动脉压（PAP）为 29mmHg。在 13 项研究中对次大面积 PE 患者的后续超声心动图检查显示 11 名患者 RV 正常，PAP 为 28mmHg。