Department of Acute Medicine, Queen Elizabeth Hospital Birmingham, Mindelsohn way, Birmingham, West Midlands.
Department of Acute Medicine, Queen Elizabeth Hospital Birmingham, Mindelsohn way, Birmingham, West Midlands, United Kingdom.
Acute Med. 2021;20(1):48-67.
BACKGROUND/OBJECTIVES: A systematic review was conducted to assess if frailty and sarcopenia were associated with poorer outcomes in older adults admitted to an acute medical unit (AMU).
Eligible studies included older adults with an unplanned admission to an AMU and included a measure of frailty or sarcopenia, completed within 72 hours of admission. Risk of bias was assessed.
Of 1659 identified articles, 16 were included (4 on sarcopenia and 12 on frailty). There was significant study heterogeneity. Overall, frailty and sarcopenia were associated with worse outcomes. Targeted interventions appeared to improve outcomes.
Current evidence suggests some benefit in screening older adults admitted to an AMU for frailty and sarcopenia. However, further studies are required before clinical adoption.
背景/目的：系统评价评估了虚弱和肌肉减少症是否与急性内科病房（AMU）收治的老年人的不良结局相关。
符合条件的研究包括无计划入住 AMU 的老年人，并在入院后 72 小时内进行了虚弱或肌肉减少症的评估。评估了风险偏倚。
在 1659 篇确定的文章中，有 16 篇被纳入（4 篇关于肌肉减少症，12 篇关于虚弱）。研究存在显著的异质性。总体而言，虚弱和肌肉减少症与不良结局相关。有针对性的干预措施似乎可以改善结局。
目前的证据表明，对入住 AMU 的老年人进行虚弱和肌肉减少症筛查可能有益。然而，在临床应用之前，还需要进一步的研究。
