Manoharan A, Hargrave M, Gordon S
Department of Clinical Haematology, St George Hospital, University of New South Wales, Sydney.
Pathology. 1988 Jan;20(1):7-9. doi: 10.3109/00313028809085188.
A leukoerythroblastic blood picture and tear drop shaped red cells are two characteristic features of myelofibrosis (MF). Following our earlier observation of an increase in the hemoglobin level with chemotherapy, we have now reviewed the pre- and post-treatment peripheral blood smears from 14 patients with MF to assess the effect of treatment on the above mentioned peripheral blood features. Our results suggest that these features are reversible with effective chemotherapy.
白细胞红细胞造血象和泪滴形红细胞是骨髓纤维化(MF)的两个特征性表现。继我们早期观察到化疗后血红蛋白水平升高之后,我们现在回顾了14例骨髓纤维化患者治疗前后的外周血涂片,以评估治疗对上述外周血特征的影响。我们的结果表明,这些特征在有效的化疗后是可逆的。