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未经治疗的牙科疾病和肺移植候补名单评估时间为囊性纤维化患者。

Untreated dental disease and lung transplant waitlist evaluation time for individuals with cystic fibrosis.

机构信息

Department of Oral Health Sciences, School of Dentistry, University of Washington, Seattle, Washington, USA.

Department of Dental Health Sciences, School of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

出版信息

Spec Care Dentist. 2021 Jul;41(4):489-497. doi: 10.1111/scd.12586. Epub 2021 Mar 22.

Abstract

AIMS

Dental clearance is typically part of the evaluation process prior to placement on the lung transplant waiting list. Individuals with cystic fibrosis (CF) are thought to be at low risk for dental disease. We hypothesized that individuals with CF in need of lung transplantation would have lower dental disease prevalence and shorter waitlist evaluation time than individuals with non-CF lung diseases.

METHODS AND RESULTS

We conducted a retrospective study of individuals who received a lung transplant between 2011 and 2017 at the University of Washington (Seattle, WA, USA) (N = 280). Untreated dental disease was assessed by the individual's dentist. Waitlist evaluation time was defined as the time, in days, from the initial evaluation by a transplant pulmonologist to placement on the lung transplant waiting list. We used logistic and linear regression models for hypothesis testing. The prevalence of untreated dental disease did not differ by CF status (p = 0.99). There was no difference in waitlist evaluation time for transplant recipients by CF status (p = 0.78) or by dental disease status (p = 0.93).

CONCLUSIONS

Our findings provide further evidence that individuals with CF are not at low risk for dental disease. Ensuring optimal oral health is important for all individuals with lung diseases.

摘要

目的

在被列入肺移植等候名单之前,通常需要进行牙科检查。囊性纤维化(CF)患者被认为患牙科疾病的风险较低。我们假设需要进行肺移植的 CF 患者的牙科疾病患病率较低,等候名单评估时间也会短于非 CF 肺部疾病患者。

方法和结果

我们对 2011 年至 2017 年期间在美国华盛顿大学(西雅图,WA,美国)接受肺移植的 280 名患者进行了回顾性研究。未治疗的牙科疾病由患者的牙医进行评估。等候名单评估时间定义为从移植肺科医生首次评估到被列入肺移植等候名单的天数。我们使用逻辑回归和线性回归模型进行假设检验。未治疗的牙科疾病的患病率不因 CF 状况而异(p=0.99)。CF 状况(p=0.78)或牙科疾病状况(p=0.93)对移植受者的等候名单评估时间没有影响。

结论

我们的研究结果进一步证明 CF 患者并非患牙科疾病的风险较低。确保所有肺部疾病患者的口腔健康都处于最佳状态非常重要。

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