Center of Pharmacological and Botanical Studies (CEFyBO), School of Medicine University of Buenos Aires (UBA)-National Research Council (CONICET), Buenos Aires, Argentina.
Center of Pharmacological and Botanical Studies (CEFyBO), School of Medicine University of Buenos Aires (UBA)-National Research Council (CONICET), Buenos Aires, Argentina.
Vitam Horm. 2021;116:363-387. doi: 10.1016/bs.vh.2021.02.003. Epub 2021 Mar 10.
Successful implantation and placentation require neoangiogenesis and the remodeling of the uterine spiral arteries. Progesterone and estradiol control various of the placental functions, but their role in vascular remodeling remains controversial. Therefore, this chapter aims to summarize the current knowledge regarding the role of steroid hormones in the uteroplacental vascular remodeling during the first trimester of gestation.
成功的着床和胎盘形成需要新血管生成和子宫螺旋动脉的重塑。孕酮和雌二醇控制着胎盘的各种功能，但它们在血管重塑中的作用仍存在争议。因此，本章旨在总结类固醇激素在妊娠早期子宫胎盘血管重塑中的作用的最新知识。
