Glatthaar E, Kleeberg H H
S Afr Med J. 1977 Oct 8;52(16):633-8.
In comparative investigations the Japanese vaccinating tool was found to be more satisfactory for BCG administration than the Heaf multipuncture apparatus. Not only were the immune responses achieved by 27 punctures made by the Japanese applicator equal to those produced by 40 punctures made by the Heaf apparatus, but the results were similar to those obtained with the intradermal method of vaccination. The Japanese applicator can be sterilized effectively, it is simple to use, durable, usable up to 100 times and cheap. All pre- and post-vaccination tuberculin testing was done intradermally with 2 tuberculin units of human PPD RT23. The studies also confirmed the high quality of the Japanese intradermal and percutaneous BCG vaccines. Administration of the potent percutaneous Japanese BCG vaccine with the Japanese applicator is an ideal, effective and safe method of BCG vaccination.
在比较研究中，发现日本的接种工具在卡介苗接种方面比希夫多针法接种器更令人满意。日本接种器进行27次针刺所产生的免疫反应不仅与希夫接种器进行40次针刺所产生的免疫反应相当，而且结果与皮内接种法相似。日本接种器可有效消毒，使用简单，耐用，可使用多达100次且价格便宜。所有接种前和接种后的结核菌素检测均采用2个结核菌素单位的人PPD RT23进行皮内注射。研究还证实了日本皮内和皮上卡介苗的高质量。使用日本接种器接种强效皮上日本卡介苗是一种理想、有效且安全的卡介苗接种方法。
