Department of Child Health and Paediatrics, Moi University College of Health Science, Eldoret, Kenya.
Academic Model Providing Access to Healthcare, Eldoret, Kenya.
PLoS One. 2021 Mar 23;16(3):e0248838. doi: 10.1371/journal.pone.0248838. eCollection 2021.
Neonatal hypothermia is a great concern with near epidemic levels globally. In Kenya, its prevalence is as high as 87% with limited local data on the associated factors such as adherence to warm chain guidelines as recommended by the World Health Organisation (WHO) is limited. This study aimed to determine the prevalence of hypothermia and level of adherence to the WHO thermal care guidelines among newborns admitted at Moi Teaching and Referral Hospital (MTRH). It adopted a prospective study design of following up neonates for the first 24 hours of admission to the MTRH newborn unit. Thermometry, interview of mothers and observation of thermal care practices was done. Descriptive and inferential statistical techniques were adopted. Specifically, Pearson's chi-square test of associations between predictors of neonatal hypothermia and management outcomes was conducted with their corresponding risk estimates at 95% confidence interval. Among the 372 participants, 64.5% (n = 240) were born at MTRH, 47.6% (177) were preterm and 53.2% (198) had birth weights below 2500 grams. Admission hypothermia was noted among 73.7% (274) and 13% (49) died on the first day of admission. Only 7.8% (29) newborns accessed optimal thermal care. Prematurity, day one mortality and adherence to the warm chain were significantly (p<0.001) associated with admission hypothermia. Inappropriate thermal appliance, inadequate clothing and late breastfeeding significantly increased the risk of neonatal hypothermia. Absence of admission hypothermia increased the likelihood of neonatal survival more than twenty-fold (AOR = 20.91, 95% CI: 2.15-153.62). Three out four neonates enrolled had admission hypothermia which was significantly associated with prematurity, lack of adherence to warm chain and increased risk of neonatal mortality on the first day of life. There was low adherence to the WHO thermal care guidelines. This should be optimized among preterm neonates to improve likelihood of survival.
新生儿低体温是一个全球性的严重问题,其流行率高达 87%。在肯尼亚,有关其相关因素的本地数据非常有限,例如世界卫生组织(WHO)推荐的温链指南的遵循情况。本研究旨在确定在莫伊教学和转诊医院(MTRH)住院的新生儿低体温的患病率以及对世卫组织热保健指南的遵守程度。它采用了前瞻性研究设计,对 MTRH 新生儿病房入院的新生儿进行了头 24 小时的随访。进行了体温测量,对母亲进行了访谈,并观察了热保健措施的实施情况。采用描述性和推断性统计技术。具体来说,对新生儿低体温的预测因素与管理结果之间的关联进行了 Pearson 卡方检验,并以 95%置信区间对应的风险估计值进行了分析。在 372 名参与者中,有 64.5%(n=240)出生于 MTRH,47.6%(177)为早产儿,53.2%(198)的出生体重低于 2500 克。有 73.7%(274)的入院新生儿体温过低,13%(49)在入院的第一天死亡。只有 7.8%(29)的新生儿接受了最佳的热保健。早产、第一天死亡率和对温链的遵守情况与入院低体温显著相关(p<0.001)。使用不当的保暖设备、衣物不足和哺乳延迟显著增加了新生儿低体温的风险。入院时没有低体温,新生儿存活的可能性增加了二十多倍(AOR=20.91,95%CI:2.15-153.62)。四分之三的入院新生儿体温过低,这与早产、不遵守温链以及第一天新生儿死亡率增加显著相关。对世卫组织热保健指南的遵循情况很低。在早产儿中应优化这一点,以提高存活的可能性。