Internal Medicine, Tepecik Training and Research Hospital, University of Health Sciences, Izmir, Turkey.
Intern Emerg Med. 2021 Nov;16(8):2105-2108. doi: 10.1007/s11739-021-02713-z. Epub 2021 Mar 23.
The relationship between insulin resistance and thyroid nodules is not clearly understood. The purpose of this study is to investigate the relationship between insülin resistance and thyroid nodules in non-diabetic patients. 410 patients who applied to the Internal Medicine outpatient clinic from June 2018 to July 2019 were reviewed retrospectively. A total of 216 non-diabetic patients were divided into two groups. The relationship of 105 patients with thyroid nodules and 110 patients without thyroid nodules with insulin resistance was investigated. Homeostasis model assessment of insulin resistance value, serum triglycerides and total cholesterol level, and the ratio of women were higher in the group with thyroid nodules (p < 0.05). There was a positive and significant relationship between homeostasis model assessment of insulin resistance value and thyroid nodules (r + 0.29, p < 0.05). In non-diabetic thyroid nodule patients, a significant relationship was detected between nodule formation and insulin resistance. However, these data must be confirmed by other studies in the future.
胰岛素抵抗与甲状腺结节之间的关系尚不清楚。本研究旨在探讨非糖尿病患者中胰岛素抵抗与甲状腺结节之间的关系。回顾性分析 2018 年 6 月至 2019 年 7 月我院内科门诊就诊的 410 例患者，其中非糖尿病患者 216 例，分为两组，分析 105 例甲状腺结节患者和 110 例无甲状腺结节患者的胰岛素抵抗关系。结果显示，甲状腺结节组的稳态模型评估的胰岛素抵抗值、血清三酰甘油和总胆固醇水平及女性比例较高（p<0.05）。稳态模型评估的胰岛素抵抗值与甲状腺结节呈正相关（r+0.29，p<0.05）。在非糖尿病甲状腺结节患者中，结节形成与胰岛素抵抗之间存在显著关系。然而，这些数据未来还需要其他研究进一步证实。
