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有袋动物尤金袋鼠育儿袋发育过程中代谢率和血液呼吸特征的变化

Changes in metabolic rates and blood respiratory characteristics during pouch development of a marsupial, Macropus eugenii.

作者信息

Baudinette R V, Gannon B J, Ryall R G, Frappell P B

机构信息

Schools of Biological Sciences, Flinders University of South Australia.

出版信息

Respir Physiol. 1988 May;72(2):219-28. doi: 10.1016/0034-5687(88)90008-4.

DOI:10.1016/0034-5687(88)90008-4
PMID:3375614
Abstract

Oxygen levels in the pouch of the tammar wallaby, Macropus eugenii, have been related to the metabolic rate of the young at pouch temperatures and the oxygen transport characteristics of its haemoglobin. Until 100 days of age, pouch young show mass-specific rates of oxygen consumption lower than predicted on the basis of body mass. This contrasts with data presented for laboratory mice. Oxygen levels in the pouch approximate atmospheric levels for the first 20 days and at times approaching pouch evacuation at 200 days. However, levels of around 17-18% occur at about the mid-point of pouch life. The oxygen-haemoglobin equilibrium curve shows a high P50 (up to 50 Torr at 36 degrees C) in the neonate, but after 2-3 weeks of age levels drop to those representative of the adult. Concentrations of 2,3-diphosphoglycerate in early pouch young are higher than in the adult animal and peak at around 30 mumol/g Hb. There is a significant decrease in the concentration of this compound with the age of the young.

摘要

帚尾袋鼩(Macropus eugenii)育儿袋内的氧气水平,与育儿袋温度下幼崽的代谢率及其血红蛋白的氧运输特性有关。在100日龄之前,育儿袋内的幼崽表现出的单位体重耗氧率低于根据体重预测的数值。这与实验室小鼠的数据形成对比。育儿袋内的氧气水平在前20天接近大气水平,在200天时有时接近育儿袋排空时的水平。然而,在育儿袋生活的中点左右,氧气水平约为17 - 18%。氧-血红蛋白平衡曲线显示,新生儿的P50值较高(36摄氏度时高达50托),但在2 - 3周龄后,该值降至成年动物的代表性水平。育儿袋早期幼崽体内2,3 - 二磷酸甘油酸的浓度高于成年动物,在约30微摩尔/克血红蛋白时达到峰值。随着幼崽年龄的增长,这种化合物的浓度显著降低。

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